The Journal of Urology
Volume 184, Issue 3 , Pages 913-917 , September 2010

Value of Real-Time Elastography Targeted Biopsy for Prostate Cancer Detection in Men With Prostate Specific Antigen 1.25 ng/ml or Greater and 4.00 ng/ml or Less

  • Friedrich Aigner

      Affiliations

    • Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria
    • Corresponding Author InformationCorrespondence: Department of Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria (telephone: ++43-512-504-82091; FAX: ++43-512-504-24823)
    • ,
  • Leo Pallwein

      Affiliations

    • Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Daniel Junker

      Affiliations

    • Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Georg Schäfer

      Affiliations

    • Department of Urology, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Gregor Mikuz

      Affiliations

    • Department of Pathology, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Florian Pedross

      Affiliations

    • Department of Medical Statistics, Informatics and Health, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Michael Josef Mitterberger

      Affiliations

    • Department of Urology, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Werner Jaschke

      Affiliations

    • Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria
    • ,
  • Ethan J. Halpern

      Affiliations

    • Department of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania
    • ,
  • Ferdinand Frauscher

      Affiliations

    • Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria

Received 11 February 2010

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225
  2. Aus G, Abbou CC, Bolla M, et al. EAU guidelines on prostate cancer (European Association of Urology). Eur Urol. 2005;48:546
  3. Scardino PT, Weaver R, Hudson MA. Early detection of prostate cancer. Hum Pathol. 1992;23:211
  4. Rifkin MD. Ultrasound of the Prostate. 3rd ed.. Philadelphia: Lippincott-Raven; 1997;
  5. Schröder FH, Carter HB, Wolters T, et al. Early detection of prostate cancer in 2007 (Part 1: PSA and PSA kinetics). Eur Urol. 2008;53:468
  6. GómezVeiga F, Ponce Reixa J, BarbagelataLópez A, et al. Current role of PSA and other markers in the diagnosis of prostate cancer. Arch Esp Urol. 2006;59:1069
  7. Krouskop TA, Wheeler TM, Kallel F, et al. Elastic moduli of breast and prostate tissues under compression. Ultrason Imaging. 1998;20:260
  8. Salomon G, Köllerman J, Thederan I, et al. Evaluation of prostate cancer detection with ultrasound real-time elastography: a comparison with step section pathological analysis after radical prostatectomy. Eur Urol. 2008;54:1354
  9. Bartsch G, Horninger W, Klocker H, et al. Tyrol Prostate Cancer Demonstration Project: early detection, treatment, outcome, incidence and mortality. BJU Int. 2008;101:809
  10. Thompson IM, Pauler DK, Goodman PJ, et al. Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0 ng per milliliter. N Engl J Med. 2004;350:2239
  11. Pallwein L, Mitterberger M, Struve P, et al. Comparison of sonoelastography guided biopsy with systematic biopsy: impact on prostate cancer detection. Eur Radiol. 2007;17:2278
  12. König K, Scheipers U, Pesavento A, et al. Initial experiences with real-time elastography guided biopsies of the prostate. J Urol. 2005;174:115
  13. Pelzer AE, Bektic J, Berger AP, et al. Are transition zone biopsies still necessary to improve prostate cancer detection? (Results from the Tyrol screening project). Eur Urol. 2005;48:916
  14. Heijmink SW, Barentsz JO. Contrast-enhanced versus systematic transrectal ultrasound-guided prostate cancer detection: an overview of techniques and a systematic review. Eur J Radiol. 2007;63:310
  15. Pallwein L, Aigner F, Faschingbauer R, et al. Prostate cancer diagnosis: value of real-time elastography. Abdom Imaging. 2008;33:729
  16. Pallwein L, Mitterberger M, Struve P, et al. Real-time elastography for detecting prostate cancer: preliminary experience. BJU Int. 2007;100:42
  17. Fütterer JJ, Heijmink SW, Scheenen TW, et al. Prostate cancer localization with dynamic contrast-enhanced MR imaging and proton MR spectroscopic imaging. Radiology. 2006;241:449
  18. Holmström B, Johansson M, Bergh A, et al. Prostate specific antigen for early detection of prostate cancer: longitudinal study. BMJ. 2009;339:b3537
  19. Boccon-Gibod LM, de Longchamps NB, Toublanc M, et al. Prostate saturation biopsy in the reevaluation of microfocal prostate cancer. J Urol. 2006;176:961
  20. Ashley RA, Inman BA, Routh JC, et al. Reassessing the diagnostic yield of saturation biopsy of the prostate. Eur Urol. 2008;53:976
  21. Lane BR, Zippe CD, Abouassaly R, et al. Saturation technique does not decrease cancer detection during followup after initial prostate biopsy. J Urol. 2008;179:1746
  22. Jones JS, Patel A, Schoenfield L, et al. Saturation technique does not improve cancer detection as an initial prostate biopsy strategy. J Urol. 2006;175:485
  23. Epstein JI, Sanderson H, Carter HB. Utility of saturation biopsy to predict insignificant cancer at radical prostatectomy. Urology. 2005;66:356
  24. Eskew LA, Bare RL, McCullough DL. Systematic 5 region prostate biopsy is superior to sextant method for diagnosing carcinoma of the prostate. J Urol. 1997;157:199

 Study received local ethical review board approval.

PII: S0022-5347(10)03545-7

doi: 10.1016/j.juro.2010.05.026

The Journal of Urology
Volume 184, Issue 3 , Pages 913-917 , September 2010

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