The Journal of Urology
Volume 184, Issue 2 , Pages 564-569 , August 2010

Family History and Risk of Recurrent Cystitis and Pyelonephritis in Women

  • Delia Scholes

      Affiliations

    • Group Health Research Institute, Group Health Cooperative, Seattle, Washington
    • Corresponding Author InformationCorrespondence and requests for reprints: Group Health Research Institute, Group Health Cooperative, 1730 Minor Ave., Suite 1600, Seattle, Washington 98101 (telephone: 206-287-2888; FAX: 206-287-2871)
    • ,
  • Thomas R. Hawn

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Washington
    • ,
  • Pacita L. Roberts

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Washington
    • ,
  • Sue S. Li

      Affiliations

    • Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • Ann E. Stapleton

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Washington
    • ,
  • Lue-Ping Zhao

      Affiliations

    • Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington
    • ,
  • Walter E. Stamm

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Washington
    • Supported by Grant 2 P01 DK053369-11 from the National Institute of Diabetes and Digestive and Kidney Diseases, and Specialized Centers of Research Grant 5 P50 DK064540-08 from the National Institute of Diabetes and Digestive and Kidney Diseases and the Office of Research on Women's Health, National Institutes of Health.
    • ,
  • Thomas M. Hooton

      Affiliations

    • Miller School of Medicine, University of Miami, Miami, Florida

Received 13 November 2009

References 

  1. Hooton TM, Scholes D, Hughes JP, et al. Prospective study of risk factors for symptomatic urinary tract infection in young women. N Engl J Med. 1996;335:468
  2. Brown PD, Foxman B. Pathogenesis of urinary tract infection: the role of sexual behavior and sexual transmission. Curr Infect Dis Rep. 2000;2:513
  3. Foxman B, Chi J. Health behavior and urinary tract infection in college-aged women. J Clin Epidemiol. 1990;43:329
  4. Ikaheimo R, Siitonen A, Heiskanen T, et al. Recurrence of urinary tract infection in a primary care setting: analysis of a 1-year follow-up of 179 women. Clin Infect Dis. 1996;22:91
  5. Foxman B, Klemstine KL, Brown PD. Acute pyelonephritis in US hospitals in 1997: hospitalization and in-hospital mortality. Ann Epidemiol. 2003;13:144
  6. Hooton T, Stamm W. Diagnosis and treatment of uncomplicated urinary tract infection. Infect Dis Clin North Am. 1997;11:551
  7. Scholes D, Hooton TM, Roberts PL, et al. Risk factors for recurrent urinary tract infection in young women. J Infect Dis. 2000;182:1177
  8. Scholes D, Hooton TM, Roberts PL, et al. Risk factors associated with acute pyelonephritis in healthy women. Ann Intern Med. 2005;142:20
  9. Strom BL, Collins M, West SL, et al. Sexual activity, contraceptive use, and other risk factors for symptomatic and asymptomatic bacteriuria (A case-control study). Ann Intern Med. 1987;107:816
  10. Cooke GS, Hill AV. Genetics of susceptibility to human infectious disease. Nat Rev Genet. 2001;2:967
  11. Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol. 2002;20:581
  12. Hill AV. The genomics and genetics of human infectious disease susceptibility. Annu Rev Genomics Hum Genet. 2001;2:373
  13. Hopkins WJ, Uehling DT, Wargowski DS. Evaluation of a familial predisposition to recurrent urinary tract infections in women. Am J Med Genet. 1999;83:422
  14. Saint S, Scholes D, Fihn SD, et al. The effectiveness of a clinical practice guideline for the management of presumed uncomplicated urinary tract infection in women. Am J Med. 1999;106:636
  15. Rubin RH, Shapiro ED, Andriole VT, et al. Evaluation of new anti-infective drugs for the treatment of urinary tract infection (Infectious Diseases Society of America and the Food and Drug Administration). Clin Infect Dis. 1992;15:S216
  16. Armstrong BK, White E, Saracci R. Principles of Exposure Measurement in Epidemiology. New York: Oxford University Press; 1992;
  17. Marcus AC. Memory aids in longitudinal health surveys: results from a field experiment. Am J Public Health. 1982;72:567
  18. Hawn TR, Scholes D, Li SS, et al. Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. PLoS One. 2009;4:e5990
  19. Lundstedt AC, Leijonhufvud I, Ragnarsdottir B, et al. Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection. J Infect Dis. 2007;195:1227
  20. Hopkins WJ, Elkahwaji JE, Heisey DM, et al. Inheritance of susceptibility to induced Escherichia coli bladder and kidney infections in female C3H/HeJ mice. J Infect Dis. 2003;187:418
  21. Finer G, Landau D. Pathogenesis of urinary tract infections with normal female anatomy. Lancet Infect Dis. 2004;4:631
  22. Hopkins WJ, Heisey DM, Lorentzen DF, et al. A comparative study of major histocompatibility complex and red blood cell antigen phenotypes as risk factors for recurrent urinary tract infections in women. J Infect Dis. 1998;177:1296
  23. Frendeus B, Godaly G, Hang L, et al. Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart. J Exp Med. 2000;192:881
  24. Tomisawa S, Kogure T, Kuroume T, et al. P blood group and proneness to urinary tract infection in Japanese children. Scand J Infect Dis. 1989;21:403
  25. Sheinfeld J, Schaeffer A, Cordon-Cardo C, et al. Association of the Lewis blood-group phenotype with recurrent urinary tract infections in women. N Engl J Med. 1989;320:773
  26. Ishitoya S, Yamamoto S, Mitsumori K, et al. Non-secretor status is associated with female acute uncomplicated pyelonephritis. BJU Int. 2002;89:851
  27. Kinane DF, Blackwell CC, Brettle RP, et al. ABO blood group, secretor state, and susceptibility to recurrent urinary tract infection in women. Br Med J (Clin Res Ed). 1982;285:7
  28. Lundstedt AC, McCarthy S, Gustafsson MC, et al. A genetic basis of susceptibility to acute pyelonephritis. PLoS One. 2007;2:e825
  29. Tabel Y, Berdeli A, Mir S. Association of TLR2 gene Arg753Gln polymorphism with urinary tract infection in children. Int J Immunogenet. 2007;34:399
  30. Karoly E, Fekete A, Banki NF, et al. Heat shock protein 72 (HSPA1B) gene polymorphism and Toll-like receptor (TLR) 4 mutation are associated with increased risk of urinary tract infection in children. Pediatr Res. 2007;61:371

 Study received Group Health Human Subjects Committee approval.

 Nothing to disclose.

 Editor's Note: This article is the fifth of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 810 and 811.

PII: S0022-5347(10)03266-0

doi: 10.1016/j.juro.2010.03.139

The Journal of Urology
Volume 184, Issue 2 , Pages 564-569 , August 2010

Article Tools