The Journal of Urology
Volume 184, Issue 1 , Pages 274-279 , July 2010

The Swedish Reflux Trial in Children: I. Study Design and Study Population Characteristics

  • Per Brandström

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • ,
  • Elisabeth Esbjörner

      Affiliations

    • Department of Pediatrics, Örebro University Hospital, Örebro, Sweden
    • ,
  • Maria Herthelius

      Affiliations

    • Department for Clinical Science, Intervention and Technology, Karolinska University Hospital, Huddinge, Sweden
    • ,
  • Gundela Holmdahl

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • ,
  • Göran Läckgren

      Affiliations

    • Section of Urology, Uppsala University Children's Hospital, Uppsala, Sweden
    • ,
  • Tryggve Nevéus

      Affiliations

    • Department of Pediatrics, Uppsala University Children's Hospital, Uppsala, Sweden
    • ,
  • Ulla Sillén

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • ,
  • Rune Sixt

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • ,
  • Ingrid Sjöberg

      Affiliations

    • Department of Pediatrics, Children's University Hospital, Lund, Sweden
    • ,
  • Eira Stokland

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • ,
  • Ulf Jodal

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • ,
  • Sverker Hansson

      Affiliations

    • Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, University of Gothenburg, Göteborg, Sweden
    • Corresponding Author InformationCorrespondence: Pediatric Uro-Nephrologic Center, Queen Silvia Children's Hospital, SE-416 85 Göteborg, Sweden

Received 30 September 2009

References 

  1. Winberg J. Management of primary vesico-ureteric reflux in children—operation ineffective in preventing progressive renal damage. Infection. 1994;22:S4
  2. Jodal U, Jacobsson B. Vesico-ureteric reflux in children (Proceedings of a state-of-the-art symposium organized by the Swedish Medical Research Council, 1997). Acta Paediatr. 1999;88(suppl.):431
  3. Jodal U, Lindberg U. Guidelines for management of children with urinary tract infection and vesico-ureteric reflux. Acta Paediatr. 1999;88(suppl.):87
  4. Bollgren I. Antibacterial prophylaxis in children with urinary tract infection. Acta Paediatr. 1999;88(suppl.):48
  5. Le Saux N, Pham B, Moher D. Evaluating the benefits of antimicrobial prophylaxis to prevent urinary tract infections in children: a systematic review. CMAJ. 2000;163:523
  6. Läckgren G, Wåhlin N, Stenberg A. Endoscopic treatment of children with vesico-ureteric reflux. Acta Paediatr. 1999;88(suppl.):62
  7. Holmdahl G, Hanson E, Hanson M, et al. Four-hour voiding observation in healthy infants. J Urol. 1996;156:1809
  8. Pocock SJ, Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics. 1975;31:103
  9. Lebowitz RL, Olbing H, Parkkulainen KV, et al. International system of radiographic grading of vesicoureteric reflux (International Reflux Study in Children). Pediatr Radiol. 1985;15:105
  10. Piepsz A, Colarinha P, Gordon I, et al. Guidelines on 99mTc-DMSA scintigraphy in children. Eur J Nucl Med. 2001;28:37
  11. Jansson UB, Hanson M, Hanson E, et al. Voiding pattern in healthy children 0 to 3 years old: a longitudinal study. J Urol. 2000;164:2050
  12. Nijman RJ. Diagnosis and management of urinary incontinence and functional fecal incontinence (encopresis) in children. Gastroenterol Clin North Am. 2008;37:731
  13. Farhat W, Bagli DJ, Capolicchio G, et al. The dysfunctional voiding scoring system: quantitative standardization of dysfunctional voiding symptoms in children. J Urol. 2000;164:1011
  14. Yeung CK, Godley ML, Dhillon HK, et al. The characteristics of primary vesico-ureteric reflux in male and female infants with prenatal hydronephrosis. Br J Urol. 1997;80:319
  15. Sjöström S, Sillén U, Bachelard M, et al. Spontaneous resolution of high grade infantile vesicoureteral reflux. J Urol. 2004;172:694
  16. Brandström P, Esbjörner E, Herthelius M, et al. The Swedish Reflux Trial in Children: III (Urinary tract infection pattern). J Urol. 2010;184:286

 Study received approval from research ethics committees at participating centers.

 Supported by Financial by grants from the West Region, Sweden and Futurum, Jönköping County Council, Sweden.

PII: S0022-5347(10)00142-4

doi: 10.1016/j.juro.2010.01.055

The Journal of Urology
Volume 184, Issue 1 , Pages 274-279 , July 2010

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