The Journal of Urology
Volume 183, Issue 5 , Pages 1853-1858 , May 2010

Effect of Amitriptyline on Symptoms in Treatment Naïve Patients With Interstitial Cystitis/Painful Bladder Syndrome

  • Harris E. Foster Jr.

      Affiliations

    • Department of Surgery, Section of Urology, Yale University, New Haven, Connecticut
    • Corresponding Author InformationCorrespondence: Department of Surgery, Urology, Yale School of Medicine, PO Box 208041, 800 Howard Ave., YPB318, New Haven, Connecticut 06520-8041
    • ,
  • Philip M. Hanno

      Affiliations

    • Division of Urology, University of Pennsylvania, Philadelphia, Pennsylvania
    • ,
  • J. Curtis Nickel

      Affiliations

    • Department of Urology, Queen's University, Kingston, Ontario, Canada
    • ,
  • Christopher K. Payne

      Affiliations

    • Urology Department, Stanford University Medical Center, Stanford, California
    • ,
  • Robert D. Mayer

      Affiliations

    • Department of Urology, University of Rochester, Rochester, New York
    • ,
  • David A. Burks

      Affiliations

    • Department of Urology, Henry Ford Hospital, Detroit, Michigan
    • ,
  • Claire C. Yang

      Affiliations

    • Department of Urology, University of Washington, Seattle, Washington
    • ,
  • Toby C. Chai

      Affiliations

    • Division of Urology, University of Maryland, Baltimore, Baltimore, Maryland
    • ,
  • Karl J. Kreder

      Affiliations

    • Department of Urology, University of Iowa, Iowa City, Iowa
    • ,
  • Kenneth M. Peters

      Affiliations

    • William Beaumont Hospital, Royal Oak, Michigan
    • ,
  • Emily S. Lukacz

      Affiliations

    • Department of Reproductive Medicine, University of California, San Diego, La Jolla, California
    • ,
  • Mary P. FitzGerald

      Affiliations

    • Departments of Obstetrics & Gynecology, and Urology, Loyola University, Maywood, Illinois
    • ,
  • Liyi Cen

      Affiliations

    • Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • J. Richard Landis

      Affiliations

    • Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Kathleen J. Propert

      Affiliations

    • Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Wei Yang

      Affiliations

    • Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • John W. Kusek

      Affiliations

    • National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
    • ,
  • Leroy M. Nyberg

      Affiliations

    • National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
    • ,
  • Interstitial Cystitis Collaborative Research Network

Received 19 August 2009

References 

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  2. van Ophoven A, Pokupic S, Heinecke A, et al. A prospective, randomized, placebo controlled, double-blind study of amitriptyline for the treatment of interstitial cystitis. J Urol. 2004;172:533
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 Supported by cooperative agreements U01 DK65209, 5U01 DK65255-06, U01 DK65271, U01 DK65213, U01 DK65214, U01 DK65215, U01 DK65178, U01 DK65190, U01 DK65192, U01 DK65255, U01 DK65267, U01 DK65271, 5U01 DK65202 from the National Institute of Diabetes and Digestive and Kidney Diseases.

 Clinical Trial Registration NCT00124306 (www.clinicaltrials.gov).

 Supplementary material for this article can be obtained at the Urological Pelvic Pain Collaborative Research Network (UPPCRN) website, www.cceb.upenn.edu/uppcrn.

 For another article on a related topic see page 2070.

 Editor's Note: This article is the fourth of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 2104 and 2105.

PII: S0022-5347(09)03405-3

doi: 10.1016/j.juro.2009.12.106

The Journal of Urology
Volume 183, Issue 5 , Pages 1853-1858 , May 2010

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