The Journal of Urology
Volume 183, Issue 5 , Pages 2070-2076, May 2010

TRPA1 Receptor Induced Relaxation of the Human Urethra Involves TRPV1 and Cannabinoid Receptor Mediated Signals, and Cyclooxygenase Activation

  • Philipp Weinhold

      Affiliations

    • Department of Urology, Ludwig-Maximilians University Hospital, Munich, Germany
    • ,
  • Christian Gratzke

      Affiliations

    • Department of Urology, Ludwig-Maximilians University Hospital, Munich, Germany
    • Department of Clinical Chemistry and Pharmacology, Lund University Hospital, Lund, Sweden
    • Corresponding Author InformationCorrespondence: Department of Urology, Ludwig-Maximilians University Hospital, Marchioninistrasse 15, 81377 Munich, Germany (telephone: 0049 89 7095 2971; FAX: 0049 7095 8890)
    • ,
  • Tomi Streng

      Affiliations

    • Department of Pharmacology, Drug Development and Therapeutics, University of Turku, Turku, Finland
    • ,
  • Christian Stief

      Affiliations

    • Department of Clinical Chemistry and Pharmacology, Lund University Hospital, Lund, Sweden
    • ,
  • Karl-Erik Andersson

      Affiliations

    • Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina
    • ,
  • Petter Hedlund

      Affiliations

    • Department of Clinical Chemistry and Pharmacology, Lund University Hospital, Lund, Sweden
    • Urological Research Institute, San Raffaele University, Milan, Italy
    • Department of Clinical Pharmacology, Linköping University Hospital, Linköping, Sweden
    • Financial interest and/or other relationship with Orthoptiz.

Received 29 August 2009 published online 19 March 2010.

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 Study received ethics committee approval from Lund, Sweden, and Munich, Germany.

 Supported by Swedish Research Council Grant 6837, The Medical Faculty of Lund (ALF), The Gester Foundation and Holger Christiansens Foundation.

PII: S0022-5347(09)03392-8

doi:10.1016/j.juro.2009.12.093

The Journal of Urology
Volume 183, Issue 5 , Pages 2070-2076, May 2010

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