The Journal of Urology
Volume 183, Issue 2 , Pages 743-751, February 2010

The miR-17-92 Cluster is Over Expressed in and Has an Oncogenic Effect on Renal Cell Carcinoma

  • Tsz-fung F. Chow

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • Marina Mankaruos

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • Andreas Scorilas

      Affiliations

    • Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Athens, Panepistimiopolis, Athens, Greece
    • ,
  • Youssef Youssef

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • Andrew Girgis

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • Sarah Mossad

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • Shereen Metias

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • Yostina Rofael

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • ,
  • R. John Honey

      Affiliations

    • Division of Urology, Department of Surgery, St. Michael's Hospital, Toronto, Ontario, Canada
    • Financial interest and/or other relationship with Cook and Pleuromed.
    • ,
  • Robert Stewart

      Affiliations

    • Division of Urology, Department of Surgery, St. Michael's Hospital, Toronto, Ontario, Canada
    • ,
  • Kenneth T. Pace

      Affiliations

    • Division of Urology, Department of Surgery, St. Michael's Hospital, Toronto, Ontario, Canada
    • Financial interest and/or other relationship with Sanofi-Synthelabo.
    • ,
  • George M. Yousef

      Affiliations

    • Department of Laboratory Medicine and Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    • Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationCorrespondence and requests for reprints: Department of Laboratory Medicine, St. Michael's Hospital, 30 Bond St., Toronto, Ontario, M5B 1W8, Canada (telephone: 416-864-6060, extension 6129; FAX: 416-864-5648)

Received 29 April 2009 published online 17 December 2009.

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 Study received approval from the research ethics board, St. Michael's Hospital, Toronto, Canada.

 Supported by Canadian Institute of Health Research Grant 86490.

 Supplementary material for this article can be obtained at http://www.stmichaelshospital.com/pdf/labs/suppl-fig-1.pdf, http://www.stmichaelshospital.com/pdf/labs/suppl-fig-2.pdf, http://www.stmichaelshospital.com/pdf/labs/suppl-tbl-1.pdf, http://www.stmichaelshospital.com/pdf/labs/suppl-tbl-2.pdf and http://www.stmichaelshospital.com/pdf/labs/suppl-tbl-3.pdf.

PII: S0022-5347(09)02627-5

doi:10.1016/j.juro.2009.09.086

The Journal of Urology
Volume 183, Issue 2 , Pages 743-751, February 2010

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