The Journal of Urology
Volume 183, Issue 2 , Pages 786-792 , February 2010

Improvement in Neurogenic Detrusor Overactivity by Peripheral C Fiber's Suppression With Cyclooxygenase Inhibitors

Received 22 April 2009

References 

  1. Maggi CA. Prostanoids as local modulators of reflex micturition. Pharmacol Res. 1992;25:13
  2. Brown WW, Zenser TV, Davis BB. Prostaglandin E2 production by rabbit urinary bladder. Am J Physiol. 1980;239:F452
  3. Khalaf IM, Lehoux JG, Elshawarby LA, et al. Release of prostaglandins into the pelvic venous blood of dogs in response to vesical distention and pelvic nerve stimulation. Invest Urol. 1979;17:244
  4. Morikawa K, Fukuoka M, Kakiuchi M, et al. Detrusor hyperreflexia induced by intravesical instillation of xylene in conscious rats. Jpn J Pharmacol. 1990;52:587
  5. Andersson KE. Pharmacology of lower urinary tract smooth muscles and penile erectile tissues. Pharmacol Rev. 1993;45:253
  6. Takeda H, Yamazaki Y, Igawa Y, et al. Effects of beta3-adrenoceptor stimulation on prostaglandin E2-induced bladder hyperactivity and on the cardiovascular system in conscious rats. Neurourol Urodyn. 2002;21:558
  7. Kim JC, Park EY, Hong SH, et al. Changes of urinary nerve growth factor and prostaglandins in male patients with overactive bladder symptom. Int J Urol. 2005;12:875
  8. Kim JC, Park EY, Seo SI, et al. Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder. J Urol. 2006;175:1773
  9. Wibberley A. Overactive bladder: targeting prostaglandins in sensory pathways. Drug Discov Today Ther Strat. 2005;2:7
  10. Saito M, Kawatani M, Kinoshita Y, et al. Effectiveness of an anti-inflammatory drug, loxoprofen, for patients with nocturia. Int J Urol. 2005;12:779
  11. Shinozaki S, Saito M, Kawatani M. Loxoprofen inhibits facilitated micturition reflex induced by acetic acid urinary bladder infusion of the rats. Biomed Res. 2005;26:29
  12. Angelico P, Guarneri L, Velasco C, et al. Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes. BJU Int. 2006;97:837
  13. Tanaka I, Akino H, Aoki Y, et al. Cyclooxygenase inhibitors improve noninflammatory overactive bladder caused by cerebral infarction because of suppression of peripheral C-fiber. J Urol, suppl. 2009;181:83;abstract 224
  14. Yaksh TL, Durant PA, Brent CR. Micturition in rats: a chronic model for study of bladder function and effect of anesthetics. Am J Physiol. 1986;251:R1177
  15. Yokoyama O, Yoshiyama M, Namiki M, et al. Influence of anesthesia on bladder hyperactivity induced by middle cerebral artery occlusion in the rat. Am J Physiol. 1997;273:R1900
  16. Nakamura Y, Yokoyama O, Komatsu K, et al. Effects of nifedipine on bladder overactivity in rats with cerebral infarction. J Urol. 1999;162:1502
  17. Hatfield RH, Mendelow AD, Perry RH, et al. Triphenyltetrazolium chloride (TTC) as a marker for ischaemic changes in rat brain following permanent middle cerebral artery occlusion. Neuropathol Appl Neurobiol. 1991;17:61
  18. Cheng CL, Ma CP, de Groat WC. Effects of capsaicin on micturition and associated reflexes in rats. Am J Physiol. 1993;265:R132
  19. Morikawa K, Ichihashi M, Kakiuchi M, et al. Effects of various drugs on bladder function in conscious rats. Jpn J Pharmacol. 1989;50:369
  20. Cao J, Boucher W, Kempuraj D, et al. Acute stress and intravesical corticotropin-releasing hormone induces mast cell dependent vascular endothelial growth factor release from mouse bladder explants. J Urol. 2006;176:1208
  21. Malinovsky JM, Le Normand L, Lepage JY. The urodynamic effects of intravenous opioids and ketoprofen in humans. Anesth Analg. 1998;87:456
  22. De Jongh R, Van Koeveringe GA, Van Kerrebroeck PE, et al. The effects of exogenous prostaglandins and the identification of constitutive cyclooxygenase I and II immunoreactivity in the normal guinea pig bladder. BJU Int. 2007;100:419
  23. Hu VY, Malley S, Dattilio A, et al. COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat. Am J Physiol Regul Integr Comp Physiol. 2003;284:R574
  24. Wibberley A, McCafferty GP, Evans C, et al. Dual, but not selective, COX-1 and COX-2 inhibitors, attenuate acetic acid-evoked bladder irritation in the anaesthetised female cat. Br J Pharmacol. 2006;148:154
  25. Linares-Fernández BE, Alfieri AB. Cyclophosphamide induced cystitis: role of nitric oxide synthase, cyclooxygenase-1 and 2, and NK1 receptors. J Urol. 2007;177:1531
  26. Jakubowski M, Levy D, Kainz V, et al. Sensitization of central trigeminovascular neurons: blockade by intravenous naproxen infusion. Neuroscience. 2007;148:573
  27. Fowler CJ. Bladder afferents and their role in the overactive bladder. Urology. 2002;59:37
  28. Maggi CA, Giuliani S, Conte B, et al. Prostanoids modulate reflex micturition by acting through capsaicin-sensitive afferents. Eur J Pharmacol. 1988;145:105
  29. Araki T, Yokoyama T, Araki M, et al. A clinical investigation of mechanism of loxoprofen, a nonsteroidal anti-inflammatory drug, for patients with nocturia. Acta Med Okayama. 2008;62:373

 Study received University of Fukui institutional animal care and use committee approval.

PII: S0022-5347(09)02610-X

doi: 10.1016/j.juro.2009.09.071

The Journal of Urology
Volume 183, Issue 2 , Pages 786-792 , February 2010