The Journal of Urology
Volume 182, Issue 6 , Pages 2555-2556 , December 2009

Cell Signaling in Kidney Cancer

References 

  1. Park JY, Lin PY, Weiss RH. Targeting the PI3K-Akt pathway in kidney cancer. Expert Rev Anticancer Ther. 2007;7:863
  2. Clark PE. The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy. Kidney Int. 2009;Epub ahead of print
  3. Bellmunt J. Future developments in renal cell carcinoma. Ann Oncol. 2009;20:i13
  4. Elrod HA, Lin YD, Yue P, et al. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway. Mol Cancer Ther. 2007;6:2029
  5. Zerp SF, Vink SR, Ruiter GA, et al. Alkylphospholipids inhibit capillary-like endothelial tube formation in vitro: antiangiogenic properties of a new class of antitumor agents. Anticancer Drugs. 2008;19:65
  6. Hutson TE, Figlin RA. Novel therapeutics for metastatic renal cell carcinoma. Cancer. 2009;115:2361
  7. Sosman J, Puzanov I. Combination targeted therapy in advanced renal cell carcinoma. Cancer. 2009;115:2368
  8. Loges S, Mazzone M, Hohensinner P, et al. Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell. 2009;15:167
  9. O'Reilly KE, Rojo F, She QB, et al. mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res. 2006;66:1500
  10. Carracedo A, Ma L, Teruya-Feldstein J, et al. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. J Clin Invest. 2008;118:3065

PII: S0022-5347(09)02514-2

doi: 10.1016/j.juro.2009.09.032

The Journal of Urology
Volume 182, Issue 6 , Pages 2555-2556 , December 2009