The Journal of Urology
Volume 182, Issue 6, Supplement , Pages S8-S13 , December 2009

Animal Models of Diabetic Uropathy

  • Firouz Daneshgari

      Affiliations

    • Corresponding Author InformationCorrespondence: Department of Urology, Case Western Reserve University, University Hospitals Medical Center, 11100 Euclid Ave., Cleveland, Ohio 44106 (telephone: 216-844-5504)
    • Current address: Department of Urology, Case Western Reserve University, University Hospitals Medical Center, 11100 Euclid Ave., Cleveland, Ohio 44106.
  • ,
  • Edward H. Leiter
  • ,
  • Guiming Liu

      Affiliations

    • Current address: Department of Urology, Case Western Reserve University, University Hospitals Medical Center, 11100 Euclid Ave., Cleveland, Ohio 44106.
  • ,
  • Jay Reeder

References 

  1. Daneshgari F, Moore C. Diabetic uropathy. Semin Nephrol. 2006;26:182
  2. National Diabetes Fact Sheet: General Information and National Estimates on Diabetes in the United States 2005. Bethesda: Centers for Disease Control and Prevention; 2005;
  3. Urologic Complications of Diabetes Mellitus in Overcoming Bladder Disease: A Strategic Plan for Research (A Report of the NIH-NIDDK Bladder Research Progress Review Group). Bethesda: National Institute of Diabetes and Digestive and Kidney Diseases, Bladder Research Progress Review Group; 2004;
  4. Jozwik M, Jozwik M. The physiological basis of pelvic floor exercises in the treatment of stress urinary incontinence. Br J Obstet Gynaecol. 1998;105:1046
  5. In: Urologic Complications of Diabetes Mellitus. Bethesda: National Institute of Diabetes and Digestive and Kidney Diseases, Bladder Research Progress Review Group; 2002;p. 133
  6. Sarma AV, Parsons JK. Diabetes and benign prostatic hyperplasia: emerging clinical connections. Curr Urol Rep. 2009;10:1527
  7. Frimodt-Moller C. Diabetic cystopathy: epidemiology and related disorders. Ann Intern Med. 1980;92:318
  8. Ueda T, Tamaki M, Kageyama S, et al. Urinary incontinence among community-dwelling people aged 40 years or older in Japan: prevalence, risk factors, knowledge and self-perception. Int J Urol. 2000;7:95
  9. Kaplan SA, Te AE, Blaivas JG. Urodynamic findings in patients with diabetic cystopathy. J Urol. 1995;153:342
  10. Brown JS, Nyberg LM, Kusek JW, et al. Proceedings of the National Institute of Diabetes and Digestive and Kidney Diseases International Symposium on Epidemiologic Issues in Urinary Incontinence in Women. Am J Obstet Gynecol. 2003;188:S77
  11. Daneshgari F, Liu G, Imrey PB. Time dependent changes in diabetic cystopathy in rats include compensated and decompensated bladder function. J Urol. 2006;176:380
  12. Liu G, Daneshgari F. Temporal diabetes- and diuresis-induced remodeling of the urinary bladder in the rat. Am J Physiol Regul Integr Comp Physiol. 2006;291:R837
  13. Kebapci N, Yenilmez A, Efe B, et al. Bladder dysfunction in type 2 diabetic patients. Neurourol Urodyn. 2007;26:814
  14. Spira A, Gowrishankar M, Halperin ML. Factors contributing to the degree of polyuria in a patient with poorly controlled diabetes mellitus. Am J Kidney Dis. 1997;30:829
  15. Mordes JP, Desemone J, Rossini AA. The BB rat. Diabetes/Metabolism Rev. 1987;3:725
  16. Melville JL, Katon W, Delaney K, et al. Urinary incontinence in US women: a population-based study. Arch Intern Med. 2005;165:537
  17. Uustal Fornell E, Wingren G, Kjolhede P. Factors associated with pelvic floor dysfunction with emphasis on urinary and fecal incontinence and genital prolapse: an epidemiological study. Acta Obstet Gynecol Scand. 2004;83:383
  18. Santaniello F, Giannantoni A, Cochetti G, et al. Body mass index and lower urinary tract symptoms in women. Arch Ital Urol Androl. 2007;79:17
  19. Han MO, Lee NY, Park HS. Abdominal obesity is associated with stress urinary incontinence in Korean women. Int Urogynecol J Pelvic Floor Dysfunct. 2006;17:35
  20. Danforth KN, Townsend MK, Lifford K, et al. Risk factors for urinary incontinence among middle-aged women. Am J Obstet Gynecol. 2006;194:339
  21. Goldberg RP, Abramov Y, Botros S, et al. Delivery mode is a major environmental determinant of stress urinary incontinence: results of the Evanston-Northwestern Twin Sisters Study. Am J Obstet Gynecol. 2005;193:2149
  22. Subak LL, Whitcomb E, Shen H, et al. Weight loss: a novel and effective treatment for urinary incontinence. J Urol. 2005;174:190
  23. Chen D, Wang MW. Development and application of rodent models for type 2 diabetes. Diabetes Obes Metab. 2005;7:307
  24. Leiter EH, Reifsnyder PC, Xiao Q, et al. Adipokine and insulin profiles distinguish diabetogenic and non-diabetogenic obesities in mice. Obesity. 2007;15:1961
  25. Haluzik M, Colombo C, Gavrilova O, et al. Genetic background (C57BL/6J versus FVB/N) strongly influences the severity of diabetes and insulin resistance in ob/ob mice. Endocrinology. 2004;145:3258
  26. Liu G, Daneshgari F. Alterations in neurogenically mediated contractile responses of urinary bladder in rats with diabetes. Am J Physiol Renal Physiol. 2005;288:F1220
  27. Daneshgari F, Huang X, Liu G, et al. Temporal differences in bladder dysfunction caused by diabetes, diuresis, and treated diabetes in mice. Am J Physiol Regul Integr Comp Physiol. 2006;290:R1728
  28. Jensen-Waern M, Andersson M, Kruse R, et al. Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism. Lab Anim. 2009;43:249
  29. Wszola M, Berman A, Fabisiak M, et al. TransEndoscopic Gastric SubMucosa Islet Transplantation (eGSM-ITx) in pigs with streptozotocine induced diabetes—technical aspects of the procedure—preliminary report. Ann Transplant. 2009;14:45
  30. Changolkar AK, Hypolite JA, Disanto M, et al. Diabetes induced decrease in detrusor smooth muscle force is associated with oxidative stress and overactivity of aldose reductase. J Urol. 2005;173:309
  31. Rees DA, Alcolado JC. Animal models of diabetes mellitus. Diabet Med. 2005;22:359
  32. Atkinson MA, Leiter EH. The NOD mouse model of type 1 diabetes: as good as it gets?. Nat Med. 1999;5:601
  33. Leiter EH, Reifsnyder PC. Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes. Diabetes. 2004;53:S4
  34. The Jackson Library: Type 2 Diabetes and Obesity. http://jaxmice.jax.org/research/diabetes/type2.htmlAccessed August 17, 2009
  35. Wijekoon EP, Hall B, Ratnam S, et al. Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes. 2005;54:3245
  36. Mizuno M, Sada T, Kato M, et al. Renoprotective effects of blockade of angiotensin II AT1 receptors in an animal model of type 2 diabetes. Hypertens Res. 2002;25:271
  37. Hoshi S, Shu Y, Yoshida F, et al. Podocyte injury promotes progressive nephropathy in Zucker diabetic fatty rats. Lab Invest. 2002;82:25
  38. Oltman CL, Richou LL, Davidson EP, et al. Progression of coronary and mesenteric vascular dysfunction in Zucker obese and Zucker diabetic fatty rats. Am J Physiol Heart Circ Physiol. 2006;291:H1780
  39. Peterson R. Personal communication. 2008;

PII: S0022-5347(09)01832-1

doi: 10.1016/j.juro.2009.07.084

The Journal of Urology
Volume 182, Issue 6, Supplement , Pages S8-S13 , December 2009