The Journal of Urology
Volume 182, Issue 3 , Pages 1108-1113 , September 2009

Successful Fertility Treatment for Klinefelter's Syndrome

Received 29 December 2008

References 

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  3. Harari O, Bourne H, Baker G, et al. High fertilization rate with intracytoplasmic sperm injection in mosaic Klinefelter's syndrome. Fertil Steril. 1995;63:182
  4. Laron Z, Dickerman Z, Zamir R, et al. Paternity in Klinefelter's syndrome—a case report. Arch Androl. 1982;8:149
  5. Terzoli G, Lalatta F, Lobbiani A, et al. Fertility in a 47,XXY patient: assessment of biological paternity by deoxyribonucleic acid fingerprinting. Fertil Steril. 1992;58:821
  6. Palermo GD, Cohen J, Rosenwaks Z. Intracytoplasmic sperm injection: a powerful tool to overcome fertilization failure. Fertil Steril. 1996;65:899
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  8. Palermo GD, Schlegel PN, Sills ES, et al. Births after intracytoplasmic injection of sperm obtained by testicular extraction from men with nonmosaic Klinefelter's syndrome. N Engl J Med. 1998;338:588
  9. Friedler S, Raziel A, Strassburger D, et al. Outcome of ICSI using fresh and cryopreserved-thawed testicular spermatozoa in patients with non-mosaic Klinefelter's syndrome. Hum Reprod. 2001;16:2616
  10. Vernaeve V, Staessen C, Verheyen G, et al. Can biological or clinical parameters predict testicular sperm recovery in 47,XXY Klinefelter's syndrome patients?. Hum Reprod. 2004;19:1135
  11. Madgar I, Dor J, Weissenberg R, et al. Prognostic value of the clinical and laboratory evaluation in patients with nonmosaic Klinefelter syndrome who are receiving assisted reproductive therapy. Fertil Steril. 2002;77:1167
  12. Koga M, Tsujimura A, Takeyama M, et al. Clinical comparison of successful and failed microdissection testicular sperm extraction in patients with nonmosaic Klinefelter syndrome. Urology. 2007;70:341
  13. Emre Bakircioglu M, Erden HF, Kaplancan T, et al. Aging may adversely affect testicular sperm recovery in patients with Klinefelter syndrome. Urology. 2006;68:1082
  14. Okada H, Goda K, Yamamoto Y, et al. Age as a limiting factor for successful sperm retrieval in patients with nonmosaic Klinefelter's syndrome. Fertil Steril. 2005;84:1662
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  16. Shabsigh A, Kang Y, Shabsigh R, et al. Clomiphene citrate effects on testosterone/estrogen ratio in male hypogonadism. J Sex Med. 2005;2:716
  17. Raman JD, Schlegel PN. Aromatase inhibitors for male infertility. J Urol. 2002;167:624
  18. Ramasamy R, Yagan N, Schlegel PN. Structural and functional changes to the testis after conventional versus microdissection testicular sperm extraction. Urology. 2005;65:1190
  19. Ostad M, Liotta D, Ye Z, et al. Testicular sperm extraction for nonobstructive azoospermia: results of a multibiopsy approach with optimized tissue dispersion. Urology. 1998;52:692
  20. Hussein A, Ozgok Y, Ross L, et al. Clomiphene administration for cases of nonobstructive azoospermia: a multicenter study. J Androl. 2005;26:787

 Study received Weill Cornell Medical College institutional review board approval.

PII: S0022-5347(09)01159-8

doi: 10.1016/j.juro.2009.05.019

The Journal of Urology
Volume 182, Issue 3 , Pages 1108-1113 , September 2009

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