The Journal of Urology
Volume 182, Issue 1 , Pages 139-144 , July 2009

Length of Positive Surgical Margin After Radical Prostatectomy as a Predictor of Biochemical Recurrence

  • Sergey Shikanov

      Affiliations

    • Nothing to disclose.
    • ,
  • Jie Song

      Affiliations

    • Nothing to disclose.
    • ,
  • Cassandra Royce

      Affiliations

    • Nothing to disclose.
    • ,
  • Hikmat Al-Ahmadie

      Affiliations

    • Nothing to disclose.
    • ,
  • Kevin Zorn

      Affiliations

    • Financial interest and/or other relationship with Intuitive Surgical and SurgRx, Inc.
    • ,
  • Gary Steinberg

      Affiliations

    • Financial interest and/or other relationship with Vysis, Bioniche and Spectrum.
    • ,
  • Gregory Zagaja

      Affiliations

    • Financial interest and/or other relationship with Intuitive Surgical.
    • ,
  • Arieh Shalhav

      Affiliations

    • Nothing to disclose.
    • ,
  • Scott Eggener

      Affiliations

    • Nothing to disclose.
    • Corresponding Author InformationCorrespondence: 5841 S. Maryland Ave., MC 6038, Chicago, Illinois 60637 (telephone: 773-702-5195; FAX: 773-702-1001)

Received 15 December 2008

References 

  1. Blute ML, Bostwick DG, Bergstralh EJ, Slezak JM, Martin SK, Amling CL, et al. Anatomic site-specific positive margins in organ-confined prostate cancer and its impact on outcome after radical prostatectomy. Urology. 1997;50:733
  2. Eastham JA, Kurolwa K, Ohorl M, Serlo AM, Gorbonos A, Maru N, et al. Prognostic significance of location of positive margins in radical prostatectomy specimens. Urology. 2007;70:965
  3. Ochiai A, Sotelo T, Troncoso P, Bhadkamkar V, Babaian RJ. Natural history of biochemical progression after radical prostatectomy based on length of a positive margin. Urology. 2008;71:308
  4. Swindle P, Eastham JA, Ohori M, Kattan MW, Wheeler T, Maru N, et al. Do margins matter? (The prognostic significance of positive surgical margins in radical prostatectomy specimens). J Urol. 2008;179:S47
  5. Menon M, Shrivastava A, Kaul S, Badani KK, Fumo M, Bhandari M, et al. Vattikuti Institute prostatectomy: contemporary technique and analysis of results. Eur Urol. 2007;51:648
  6. Patel VR, Thaly R, Shah K. Robotic radical prostatectomy: outcomes of 500 cases. BJU Int. 2007;99:1109
  7. Smith JA, Chan RC, Chang SS, Herrell SD, Clark PE, Baumgartner R, et al. A comparison of the incidence and location of positive surgical margins in robotic assisted laparoscopic radical prostatectomy and open retropubic radical prostatectomy. J Urol. 2007;178:2385
  8. Weizer AZ, Ye Z, Hollingsworth JM, Dunn RL, Shah RB, Wolf JS, et al. Adoption of new technology and healthcare quality: surgical margins after robotic prostatectomy. Urology. 2007;70:96
  9. Zorn KC, Gofrit ON, Orvieto MA, Mikhail AA, Zagaja GP, Shalhav AL. Robotic-assisted laparoscopic prostatectomy: functional and pathologic outcomes with interfascial nerve preservation. Eur Urol. 2007;51:755
  10. Humphrey PA. Complete histologic serial sectioning of a prostate gland with adenocarcinoma. Am J Surg Pathol. 1993;17:468
  11. Ficarra V, Cavalleri S, Novara G, Aragona M, Artibani W. Evidence from robot-assisted laparoscopic radical prostatectomy: a systematic review. Eur Urol. 2007;51:45
  12. Yossepowitch O, Bjartell A, Eastham JA, Graefen M, Guillonneau BD, Karakiewicz PI, et al. Positive surgical margins in radical prostatectomy: outlining the problem and its long-term consequences. Eur Urol. 2008;55:87
  13. Aydin H, Tsuzuki T, Hernandez D, Walsh PC, Partin AW, Epstein JI. Positive proximal (bladder neck) margin at radical prostatectomy confers greater risk of biochemical progression. Urology. 2004;64:551
  14. Watson RB, Civantos F, Soloway MS. Positive surgical margins with radical prostatectomy: detailed pathological analysis and prognosis. Urology. 1996;48:80
  15. Obek C, Sadek S, Lai SH, Civantos F, Rubinowicz D, Soloway MS. Positive surgical margins with radical retropubic prostatectomy: anatomic site-specific pathologic analysis and impact on prognosis. Urology. 1999;54:682

 Editor's Note: This article is the third of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 402 and 403.

 For another article on a related topic see page 317.

PII: S0022-5347(09)00577-1

doi: 10.1016/j.juro.2009.02.139

The Journal of Urology
Volume 182, Issue 1 , Pages 139-144 , July 2009

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