The Journal of Urology
Volume 181, Issue 3 , Pages 1046-1053, March 2009

Surgical Apgar Outcome Score: Perioperative Risk Assessment for Radical Cystectomy

  • Sandip M. Prasad

      Affiliations

    • Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts
  • ,
  • Marcos Ferreria

      Affiliations

    • Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts
  • ,
  • Alexander M. Berry

      Affiliations

    • Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts
  • ,
  • Stuart R. Lipsitz

      Affiliations

    • Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, Massachusetts
  • ,
  • Jerome P. Richie

      Affiliations

    • Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts
    • Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts
    • Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
  • ,
  • Atul A. Gawande

      Affiliations

    • Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts
  • ,
  • Jim C. Hu

      Affiliations

    • Brigham and Women's Hospital, Boston, Massachusetts
    • Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
    • Corresponding Author InformationCorrespondence: Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts (telephone: 617-732-6907; FAX: 617-566-3475)

Received 23 July 2008 published online 15 January 2009.

Purpose

Currently objective perioperative risk assessment metrics are lacking for radical cystectomy. Using a simple 10-point scale similar to neonatal Apgar assessment we evaluated whether a surgical outcome score calculated immediately after radical cystectomy would predict major complications and mortality.

Materials and Methods

We identified 155 consecutive radical cystectomies performed between 2005 and 2007 at our institution. Data were collected on 45 preoperative and intraoperative variables. We used a framework established by the National Surgical Quality Improvement Program to evaluate major complications within 30 days of surgery. We used a 10-point scoring system that had been previously validated in general and vascular surgery populations, comprising estimated blood loss, lowest heart rate and lowest mean arterial pressure.

Results

A total of 40 (26%) patients undergoing radical cystectomy experienced a major complication within 30 days of the operation. There was a progressive decrease in complications with increasing surgical Apgar score, in that patients with a low vs a high Apgar score were more likely to experience complications (OR 6.9, 95% CI 1.9-24.2). Coronary artery disease, American Society of Anesthesiologists class, intraoperative blood transfusion, volume of intravenous fluid administered and female gender were also associated with major complications (p <0.05).

Conclusions

In patients undergoing radical cystectomy the surgical Apgar score predicts major postoperative complications and death. This simple and objective postoperative metric may be used to dictate the intensity of care. Prospective studies are needed to determine whether treatment decisions based on this scoring system improve radical cystectomy outcomes.

Key Words: bladder, cystectomy, prognosis, perioperative complications, outcome and process assessment (health care)

Abbreviations and Acronyms: ASA, American Society of Anesthesiologists, EBL, estimated blood loss, HR, heart rate, MAP, mean arterial pressure, NSQIP, National Surgical Quality Improvement Program, RC, radical cystectomy, SOS, surgical outcome score

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 30.00 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

 Study received institutional review board approval.

PII: S0022-5347(08)03013-9

doi:10.1016/j.juro.2008.10.165

The Journal of Urology
Volume 181, Issue 3 , Pages 1046-1053, March 2009