The Journal of Urology
Volume 181, Issue 1 , Pages 29-34 , January 2009

Histopathological Characteristics of Localized Renal Cell Carcinoma Correlate With Tumor Size: A SEER Analysis

  • Jason Rothman

      Affiliations

    • Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    • ,
  • Brian Egleston

      Affiliations

    • Department of Biostatistics, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    • ,
  • Yu-Ning Wong

      Affiliations

    • Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    • ,
  • Kevan Iffrig

      Affiliations

    • Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    • ,
  • Steve Lebovitch

      Affiliations

    • Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    • ,
  • Robert G. Uzzo

      Affiliations

    • Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    • Corresponding Author InformationCorrespondence: Department of Urologic Oncology, Fox Chase Cancer Center, 333 Cottman Ave., Philadelphia, Pennsylvania 19111-2497 (telephone: 215-728-3501; FAX: 215-214-1734)

Received 6 May 2008

References 

  1. Chow WH, Devesa SS, Warren JL, Fraumeni JF. Rising incidence of renal cell cancer in the United States. JAMA. 2000;281:1628
  2. Jayson M, Sanders H. Increased incidence of serendipitously discovered renal cell carcinoma. Urology. 1998;51:203
  3. Chawla SN, Crispen PL, Hanlon AL, Greenberg RE, Chen DY, Uzzo RG. The natural history of observed enhancing renal masses: meta-analysis and review of the world literature. J Urol. 2006;175:425
  4. Volpe A, Kachura JR, Geddie WR, Evans AJ, Gharajeh A, Saravanan A, et al. Techniques, safety, and accuracy of sampling of renal tumors by fine needle aspiration and core biopsy. J Urol. 2007;178:379
  5. Surveillance, Epidemiology and End Results (SEER) Program Public-Use Data (1973–2004), National Cancer Institute, Division of Cancer Control and Population Sciences, Surveillance Research Program, Cancer Statistics Branch. www.seer.cancer.govAccessed November 13, 2007
  6. Harrell FE. Regression Modeling Strategies. New York: Springer; 2001;chapt 2
  7. Remzi M, Katzenbeisser D, Waldert M, Klingler HC, Susani M, Memarsadeghi M, et al. Renal tumor size measured radiologically before surgery is an unreliable variable for predicting histopathological features: benign tumours are not necessarily small. BJU Int. 2007;99:1002
  8. Kuczyk M, Wegener G, Merseburger AS, Oelke M, Zumbragel A, Bokemeyer C, et al. Impact of tumor size on the long-term survival of patients with early stage renal cell cancer. World J Urol. 2005;23:50
  9. Frank I, Blute ML, Cheville JC, Lohse CM, Weaver AL, Zincke H. Solid renal tumors: an analysis of pathological features related to tumor size. J Urol. 2003;170:2217
  10. Duchene DA, Lotan Y, Cadeddu JA, Sagalowsky AI, Koeneman KS. Histopathology of surgically managed renal tumors: analysis of a contemporary series. Urology. 2003;62:827
  11. Schlomer B, Figenshau RS, Yan Y, Venkatesh R, Bhayani SB. Pathological features of renal neoplasms classified by size and symptomatology. J Urol. 2006;176:1317
  12. Tabibi A, Parvin M, Abdi H, Bashtar R, Zamani N, Abadpour B. Correlation between size of renal cell carcinoma and its grade, stage, and histological subtype. J Urol. 2007;4:10
  13. Pahernik S, Ziegler S, Roos F, Melchior SW, Thuroff JW. Small renal tumors: correlation of clinical and pathologic features with tumor size. J Urol. 2007;178:414
  14. Hsu RM, Chan DY, Siegelman SS. Small renal cell carcinomas: correlation of size with tumor stage, nuclear grade, and histologic subtype. AJR Am J Roentgenol. 2004;182:551
  15. Remzi M, Ozsoy M, Klingler H, Susani M, Waldert M, Seitz C, et al. Are small renal tumors harmless? (Analysis of histopathological features according to tumors 4 cm or less in diameter). J Urol. 2006;176:896
  16. Patard J, Pantuck AJ, Crepel M, Lam JS, Bellec L, Albouy B, et al. Morbidity and clinical outcome of nephron-sparing surgery in relation to tumour size and indication. Eur Urol. 2007;52:148
  17. Kunkle DA, Egleston BL, Uzzo RG. Excise, ablate or observe: the small renal mass dilemma—a meta-analysis and review. J Urol. 2008;179:1227
  18. Huang WC, Levey AS, Serio AM, Snyder M, Vickers AJ, Raj GV, et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumors: a retrospective cohort study. Lancet Oncol. 2006;7:735

PII: S0022-5347(08)02427-0

doi: 10.1016/j.juro.2008.09.009

The Journal of Urology
Volume 181, Issue 1 , Pages 29-34 , January 2009

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