The Journal of Urology
Volume 181, Issue 1 , Pages 379-386, January 2009

GRC-6211, a New Oral Specific TRPV1 Antagonist, Decreases Bladder Overactivity and Noxious Bladder Input in Cystitis Animal Models

  • Ana Charrua

      Affiliations

    • Universidade do Porto, Porto, Portugal
    • ,
  • Célia D. Cruz

      Affiliations

    • Universidade do Porto, Porto, Portugal
    • ,
  • Shridhar Narayanan

      Affiliations

    • Department of Biological Research, Glenmark Pharmaceuticals, Ltd., Navi Mumbai, India
    • Financial interest and/or other relationship with Glenmark Pharmaceutical.
    • ,
  • Laxmikant Gharat

      Affiliations

    • Department of Discovery Chemistry, Glenmark Pharmaceuticals, Ltd., Navi Mumbai, India
    • Financial interest and/or other relationship with Glenmark Pharmaceutical.
    • ,
  • Srinivas Gullapalli

      Affiliations

    • Department of Biological Research, Glenmark Pharmaceuticals, Ltd., Navi Mumbai, India
    • Financial interest and/or other relationship with Glenmark Pharmaceutical.
    • ,
  • Francisco Cruz

      Affiliations

    • Institute of Histology and Embryology, Faculty of Medicine and Instituto de Biologia Molecular e Celular, Porto, Portugal
    • Department of Urology, Hospital de São João, Porto, Portugal
    • ,
  • António Avelino

      Affiliations

    • Universidade do Porto, Porto, Portugal
    • Corresponding Author InformationCorrespondence: Institute of Histology and Embryology, Faculty of Medicine of Porto, Universidade do Porto, Porto, Portugal (FAX: 225513655)

Received 2 April 2008 published online 17 November 2008.

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 Study was performed according to the European Communities Council Directive of 24 November 1986 (86/609/EEC).

 Supported by POCI/SAU-NEU/55983/2004 from FCT, Portugal and Glenmark Pharmaceuticals, Ltd., India.

PII: S0022-5347(08)02413-0

doi:10.1016/j.juro.2008.08.121

The Journal of Urology
Volume 181, Issue 1 , Pages 379-386, January 2009

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