The Journal of Urology
Volume 180, Issue 1 , Pages 398-405 , July 2008

Morphology, Calcium Signaling and Mechanical Activity in Human Ureter

  • Rachel V. Floyd

      Affiliations

    • Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Liverpool, United Kingdom
    • ,
  • Ludmylla Borisova

      Affiliations

    • Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Liverpool, United Kingdom
    • ,
  • Ali Bakran

      Affiliations

    • Royal Liverpool University Hospital, Liverpool, United Kingdom
    • ,
  • C. Anthony Hart

      Affiliations

    • Department of Medical Microbiology and Genitourinary Medicine, University of Liverpool, Liverpool, United Kingdom
    • Deceased.
    • ,
  • Susan Wray

      Affiliations

    • Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Liverpool, United Kingdom
    • ,
  • Theodor V. Burdyga

      Affiliations

    • Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Liverpool, United Kingdom
    • Corresponding Author InformationCorrespondence: Department of Physiology, University of Liverpool, Liverpool, L69 3BX, United Kingdom (telephone: 0151 794 4971; FAX: 0151 794 5321).

Received 16 October 2007

References 

  1. Yamaguchi O, Kobayashi R. Relationship between maximum active stress and contractile protein contents in the chronically obstructed ureter. J Urol. 1984;132:809
  2. Hanna MK, Jeffs RD, Sturgess JM, Barkin M. Ureteral structure and ultrastructure. Part I. The normal human ureter. J Urol. 1976;116:718
  3. Pak CY. Kidney stones. Lancet. 1998;351:1797
  4. Porpiglia F, Ghignone G, Fiori C, Fontana D, Scarpa RM. Nifedipine versus tamsulosin for the management of lower ureteral stones. J Urol. 2004;172:568
  5. Micali S, Grande M, Sighinolfi MC, De SS, Bianchi G. Efficacy of expulsive therapy using nifedipine or tamsulosin, both associated with ketoprofene, after shock wave lithotripsy of ureteral stones. Urol Res. 2007;35:133
  6. Burdyga TV, Taggart MJ, Wray S. Major difference between rat and guinea-pig ureter in the ability of agonists and caffeine to release Ca2+ and influence force. J Physiol Lond. 1995;489:327
  7. Burdyga TV, Taggart MJ, Wray S. An investigation into the mechanism whereby pH affects tension in guinea-pig ureteric smooth muscle. J Physiol Lond. 1996;493:865
  8. Burdyga T, Wray S. Action potential refractory period in ureter smooth muscle is set by Ca sparks and BK channels. Nature. 2005;436:559
  9. Wray S, Burdyga T, Noble K. Calcium signalling in smooth muscle. Cell Calcium. 2005;397:
  10. Wray S, Jones K, Kupittayanant S, Matthew AJG, Monir-Bishty E, Noble K, et al. Calcium signalling and uterine contractility. J Soc Gynecol Invest. 2003;10:252
  11. Floyd RV, Mason SL, Proudman CJ, German AJ, Marples D, Mobasheri A. Expression and nephron segment specific distribution of major renal aquaporins (AQP1-4) in Equus caballus, the domestic horse. Am J Physiol Regul Integr Comp Physiol. 2007;293:R484
  12. Sahin A, Erdemli I, Bakkaloglu M, Ergen A, Basar I, Remzi D. The effect of nifedipine and verapamil on rhythmic contractions of human isolated ureter. Arch Int Physiol Biochim Biophys. 1993;101:245
  13. Potenzoni D, Zappia L, Sacchini P, Bezzi E. Effects of rociverine on the human ureter: in vivo and in vitro experimental study. Pharmacol Res Commun. 1984;16:765
  14. Murnaghan GF. Experimental investigation of the dynamics of the normal and dilated ureter. Br J Urol. 1957;29:403
  15. Butcher HR, Sleator W. A study of the electrical activity of intact and partially mobilized human ureters. J Urol. 1955;73:970
  16. Libertino JA, Weiss RM. Ultrastructure of human ureter. J Urol. 1972;108:71
  17. Dellabella M, Milanese G, Muzzonigro G. Randomized trial of the efficacy of tamsulosin, nifedipine and phloroglucinol in medical expulsive therapy for distal ureteral calculi. J Urol. 2005;174:167
  18. Davenport K, Timoney AG, Keeley FX. A comparative in vitro study to determine the beneficial effect of calcium-channel and alpha(1)-adrenoceptor antagonism on human ureteric activity. BJU Int. 2006;98:651
  19. De Moura RS, De LemosNeto M. Effects of potassium channel modulators cromakalim, tetraethylammonium and glibenclamide on the contractility of the isolated human ureter. J Urol. 1996;156:276
  20. Burdyga T, Wray S, Noble K. In situ Ca signaling: no Ca sparks detected in rat myometrium. Ann N Y Acad Sci. 2007;1101:85

 Study received local ethical approval.

 Supported by Mersey Kidney Research (RVF).

PII: S0022-5347(08)00538-7

doi: 10.1016/j.juro.2008.02.045

The Journal of Urology
Volume 180, Issue 1 , Pages 398-405 , July 2008

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