The Journal of Urology
Volume 179, Issue 4 , Pages 1461-1469 , April 2008

Terazosin Therapy for Patients With Female Lower Urinary Tract Symptoms: A Randomized, Double-Blind, Placebo Controlled Trial

Presented at annual meeting of American Urological Association, Anaheim, California, May 19–24, 2007.

  • Bee Yean Low

      Affiliations

    • School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia
    • Financial interest and/or other relationship with Abbott Laboratories Malaysia.
    • ,
  • Men Long Liong

      Affiliations

    • Department of Urology, Lam Wah Ee Hospital, Penang, Malaysia
    • ,
  • Kah Hay Yuen

      Affiliations

    • School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia
    • Corresponding Author InformationCorrespondence: School of Pharmaceutical Sciences, University of Science Malaysia, Jalan Sungai Dua, Minden, Pulau Pinang 11800 Malaysia.
    • ,
  • Christopher Chee

      Affiliations

    • Department of Urology, Specialist Medical Centre, New South Wales, Australia
    • Consultant urologist at Pantai Mutiara Hospital when study was conducted, subsequently became a consultant urologist at Specialist Medical Centre, New South Wales, Australia.
    • ,
  • Wing Seng Leong

      Affiliations

    • Department of Urology, Lam Wah Ee Hospital, Penang, Malaysia
    • ,
  • Wooi Loong Chong

      Affiliations

    • Department of Urology, Metro Hospital, Kedah, Malaysia
    • Financial interest and/or other relationship with Metro Specialist Hospital.
    • ,
  • Nurzalina Abdul Karim Khan

      Affiliations

    • School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia
    • Financial interest and/or other relationship with Nutriscience Biotechnology (private limited).
    • ,
  • Phaik Yeong Cheah

      Affiliations

    • Clinical Trials & Research Governance, University of Oxford, United Kingdom
    • Graduate student when study was initiated, subsequently employed by Abbott Laboratories, Malaysia. Currently employed by Oxford University, United Kingdom.
    • ,
  • Ker Keong Liong

      Affiliations

    • International Medical University, Kuala Lumpur, Malaysia

Received 28 July 2007

References 

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  2. Yu HJ, Chen J, Lai MK, Chan KA, Chie WC. High prevalence of voiding symptoms in Taiwanese women. Br J Urol. 1998;82:520
  3. Moller LA, Lose G, Jorgensen T. The prevalence and bothersomeness of lower urinary tract symptoms in women 40–60 years of age. Acta Obstet Gynecol Scand. 2000;79:298
  4. Boyle P, Robertson C, Mazzetta C, Keech M, Hobbs FDR, Fourcade R, et al. The prevalence of lower urinary tract symptoms in men and women in four centres. BJU Int. 2003;92:409
  5. Low BY, Liong ML, Yuen KH, Chong WL, Chee C, Leong WS, et al. Study of prevalence, treatment-seeking behavior and risk factors of women with lower urinary tract symptoms in Northern Malaysia. Urology. 2006;68:751
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  11. Schwinn DA. Novel role for a1-adrenergic receptor subtypes in lower urinary tract symptoms. BJU Int. 2000;86:11
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  15. Michel MC, Schafers RF, Goepel M. A-blockers and lower urinary tract function: more than smooth muscle relaxation?. BJU Int. 2000;86:23
  16. Casagrande JT, Pike MC. An improved approximate formula for calculating sample sizes for comparing binomial distributions. Biometrics. 1978;34:483
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  18. Ko DSC, Fenster HN, Chambers K, Sullivan LD, Jens M, Goldenberg LS. The correlation of multichannel urodynamic pressure-flow studies and American Urological Association Symptom Index in the evaluation of benign prostatic hyperplasia. J Urol. 1995;154:396
  19. Kaplan SA, Reis RB. Significant correlation of the American Urological Association Symptom Score and a novel urodynamic parameter: detrusor contraction duration. J Urol. 1996;156:1668
  20. Buzelin JM, Fonteyne E, Kontturi M, Witjes WPJ, Khan AS European Tamsulosin Study Group. Comparison of tamsulosin with alfuzosin in the treatment of patients with lower urinary tract symptoms suggestive of bladder outlet obstruction (symptomatic benign prostatic hyperplasia). Br J Urol. 1997;80:597

 For another article on a related topic see pages 1598 and 1603.

 Supported by an unrestricted grant from Abbott Laboratories, Malaysia.

PII: S0022-5347(07)03099-6

doi: 10.1016/j.juro.2007.11.060

The Journal of Urology
Volume 179, Issue 4 , Pages 1461-1469 , April 2008

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