The Journal of Urology
Volume 179, Issue 2 , Pages 405-407 , February 2008

Vesicoureteral Reflux: the RIVUR Study and the Way Forward

  • Saul P. Greenfield

      Affiliations

    • Department of Pediatric Urology, Women & Children’s Hospital of Buffalo, Buffalo, New York
    • ,
  • Russell W. Chesney

      Affiliations

    • Le Bonheur Children’s Medical Center, Memphis, Tennessee
    • ,
  • Myra Carpenter

      Affiliations

    • University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    • ,
  • Marva Moxey-Mims (member of the RIVUR Steering Committee)

      Affiliations

    • National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
    • ,
  • Leroy Nyberg (member of the RIVUR Steering Committee)

      Affiliations

    • National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
    • ,
  • Alejandro Hoberman

      Affiliations

    • Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania
    • ,
  • Ron Keren

      Affiliations

    • Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
    • ,
  • Ranjiv Matthews

      Affiliations

    • Johns Hopkins School of Medicine, Baltimore, Maryland
    • ,
  • Tej Mattoo

      Affiliations

    • Wayne State University School of Medicine, Detroit, Michigan

References 

  1. Lenaghan D, Whitaker JG, Jensen F, Stephens FD. The natural history of reflux and long-term effects of reflux on the kidney. J Urol. 1976;115:728
  2. O’Donnell B, Moloney MA, Lynch V. Vesico-ureteric reflux in infants and children: results of “supervision”, chemotherapy and surgery. Br J Urol. 1969;41:6
  3. Birmingham Reflux Study Group. Prospective trial of operative versus non-operative treatment of severe vesicoureteric reflux in children: five years’ observation. Br Med J. 1987;295:237
  4. International Reflux Study Committee. Medical versus surgical treatment of primary vesicoureteral reflux: a prospective international reflux study in children. J Urol. 1981;125:277
  5. Cooper CS, Chung BI, Kirsch AJ, Canning DA, Snyder HM. The outcome of stopping prophylactic antibiotics in older children with vesicoureteral reflux. J Urol. 2000;163:269
  6. Thompson RH, Chen JJ, Pugach J, Naseeer S, Steinhardt GF. Cessation of prophylactic antibiotics for managing persistent vesicoureteral reflux. J Urol. 2001;166:1465
  7. Garin EH, Olavarria F, Garcia Nieto V, Valenciano B, Campos A, Young L. Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study. Pediatrics. 2006;117:626
  8. Craig JC, Irwig LM, Knight JF, Roy JP. Does treatment of vesicoureteric reflux in childhood prevent end-stage renal disease attributable to reflux nephropathy?. Pediatrics. 2000;105:1236
  9. Wheeler D, Vimalachandra D, Hodson EM, Roy LP, Smith G, Craig JC. Antibiotics and surgery for vesicoureteric reflux: a meta-analysis of randomised controlled trials. Arch Dis Child. 2003;88:688
  10. Reddy PP, Evans MT, Hughes PA, Dangman B, Cooper J, Lepow ML, et al. Antimicrobial prophylaxis in children with vesico-ureteral reflux: a randomized prospective study of continuous therapy vs intermittent therapy vs surveillance. Pediatrics. 1997;100(suppl.):555
  11. Farhat W, McLorie GA, O’Reilly S, Khoury A, Bagli DJ. Reliability of the pediatric dysfunctional voiding symptom score in monitoring response to behavioral modification. Can J Urol. 2001;8:1401
  12. Benninga M, Candy DC, Catto-Smith AG, Clayden G, Loening-Baucke V, Di Lorenzo C, et al. The Paris Consensus on Childhood Constipation Terminology (PACCT) Group. J Pediatr Gastroenterol Nutr. 2005;40:273

PII: S0022-5347(07)02881-9

doi: 10.1016/j.juro.2007.10.100

The Journal of Urology
Volume 179, Issue 2 , Pages 405-407 , February 2008

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