The Journal of Urology
Volume 179, Issue 2 , Pages 468-473 , February 2008

Radical Nephrectomy for pT1a Renal Masses May be Associated With Decreased Overall Survival Compared With Partial Nephrectomy

  • R. Houston Thompson

      Affiliations

    • Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota
    • Corresponding Author InformationCorrespondence: Department of Urology, Mayo Clinic, 200 First St. Southwest, Rochester, Minnesota 55905 (telephone: 507-284-9983; FAX: 507-284-4951).
    • ,
  • Stephen A. Boorjian

      Affiliations

    • Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota
    • ,
  • Christine M. Lohse

      Affiliations

    • Department of Health Sciences Research, Mayo Medical School and Mayo Clinic, Rochester, Minnesota
    • ,
  • Bradley C. Leibovich

      Affiliations

    • Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota
    • ,
  • Eugene D. Kwon

      Affiliations

    • Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota
    • ,
  • John C. Cheville

      Affiliations

    • Department of Laboratory Medicine and Pathology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota
    • ,
  • Michael L. Blute

      Affiliations

    • Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, Minnesota

Received 31 May 2007

References 

  1. Robson CJ, Churchill BM, Anderson W. The results of radical nephrectomy for renal cell carcinoma. J Urol. 1969;101:297
  2. Zincke H, Engen DE, Henning KM, McDonald MW. Treatment of renal cell carcinoma by in situ partial nephrectomy and extracorporeal operation with autotransplantation. Mayo Clin Proc. 1985;60:651
  3. Novick AC, Streem S, Montie JE, Pontes JE, Siegel S, Montague DK, et al. Conservative surgery for renal cell carcinoma: a single-center experience with 100 patients. J Urol. 1989;141:835
  4. Thompson RH, Frank I, Lohse CM, Saad IR, Fergany A, Zincke H, et al. The impact of ischemia time during open nephron sparing surgery on solitary kidneys: a multi-institutional study. J Urol. 2007;177:471
  5. Leibovich BC, Blute ML, Cheville JC, Lohse CM, Weaver AL, Zincke H. Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy. J Urol. 2004;171:1066
  6. Huang WC, Levey AS, Serio AM, Snyder M, Vickers AJ, Raj GV, et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study. Lancet Oncol. 2006;7:735
  7. Patard JJ, Shvarts O, Lam JS, Pantuck AJ, Kim HL, Ficarra V, et al. Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience. J Urol. 2004;171:2181
  8. Lau WK, Blute ML, Weaver AL, Torres VE, Zincke H. Matched comparison of radical nephrectomy vs nephron-sparing surgery in patients with unilateral renal cell carcinoma and a normal contralateral kidney. Mayo Clin Proc. 2000;75:1236
  9. Becker F, Siemer S, Humke U, Hack M, Ziegler M, Stockle M. Elective nephron sparing surgery should become standard treatment for small unilateral renal cell carcinoma: Long-term survival data of 216 patients. Eur Urol. 2006;49:308
  10. Lee CT, Katz J, Shi W, Thaler HT, Reuter VE, Russo P. Surgical management of renal tumors 4 cm. or less in a contemporary cohort. J Urol. 2000;163:730
  11. Miller DC, Hollingsworth JM, Hafez KS, Daignault S, Hollenbeck BK. Partial nephrectomy for small renal masses: an emerging quality of care concern?. J Urol. 2006;175:853
  12. Nuttall M, Cathcart P, van der Meulen J, Gillatt D, McIntosh G, Emberton M. A description of radical nephrectomy practice and outcomes in England: 1995–2002. BJU Int. 2005;96:58
  13. Thompson RH, Leibovich BC, Lohse CM, Zincke H, Blute ML. Complications of contemporary open nephron sparing surgery: a single institution experience. J Urol. 2005;174:855
  14. Gill IS, Matin SF, Desai MM, Kaouk JH, Steinberg A, Mascha E, et al. Comparative analysis of laparoscopic versus open partial nephrectomy for renal tumors in 200 patients. J Urol. 2003;170:64
  15. Lane BR, Gill IS. 5-Year outcomes of laparoscopic partial nephrectomy. J Urol. 2007;177:70
  16. Fried LF, Biggs ML, Shlipak MG, Seliger S, Kestenbaum B, Stehman-Breen C, et al. Association of kidney function with incident hip fracture in older adults. J Am Soc Nephrol. 2007;18:282
  17. Thompson RH. Radical nephrectomy: too radical for small renal masses?. Lancet. 2006;368:823
  18. Lesage K, Joniau S, Fransis K, Van Poppel H. Comparison between open partial and radical nephrectomy for renal tumours: perioperative outcome and health-related quality of life. Eur Urol. 2007;51:614
  19. Uzzo RG, Wei JT, Hafez K, Kay R, Novick AC. Comparison of direct hospital costs and length of stay for radical nephrectomy versus nephron-sparing surgery in the management of localized renal cell carcinoma. Urology. 1999;54:994
  20. McKiernan JM, Teschendorf B, Katz J, Herr HW, Russo P. A comparison of hospital-based charges following partial and radical nephrectomy. Urol Oncol. 2002;7:3

 Study received institutional review board approval.

PII: S0022-5347(07)02579-7

doi: 10.1016/j.juro.2007.09.077

The Journal of Urology
Volume 179, Issue 2 , Pages 468-473 , February 2008

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