The Journal of Urology
Volume 178, Issue 2 , Pages 602-607 , August 2007

New Insights Into the Pathogenesis of Penile Shortening After Radical Prostatectomy and the Role of Postoperative Sexual Function

  • Paolo Gontero

      Affiliations

    • Urologia 1, Università degli Studi di Torino, Torino, Italy
    • Corresponding Author InformationCorrespondence: Dipartimento di Discipline Medico Chirurgiche, University of Turin, Urologia 1, San Giovanni Battista Hospital, C.so Dogliotti, 14 Torino (telephone/FAX: 011.6335581; mobile telephone: 347.8600447).
    • ,
  • Mario Galzerano

      Affiliations

    • SCDU Epidemiologia dei Tumori Dipartimento di Scienze Mediche, Università del Piemonte Orientale, Novara, Italy
    • ,
  • Riccardo Bartoletti

      Affiliations

    • Clinica Urologica, Ospedale S Maria Annunziata, Firenze, Italy
    • ,
  • Corrado Magnani

      Affiliations

    • SCDU Epidemiologia dei Tumori Dipartimento di Scienze Mediche, Università del Piemonte Orientale, Novara, Italy
    • ,
  • Alessandro Tizzani

      Affiliations

    • Urologia 1, Università degli Studi di Torino, Torino, Italy
    • ,
  • Bruno Frea

      Affiliations

    • Clinica Urologica, Università di Udine, Udine, Italy
    • ,
  • Nicola Mondaini

      Affiliations

    • Clinica Urologica, Ospedale S Maria Annunziata, Firenze, Italy

Received 19 December 2006

References 

  1. Munding MD, Wessells HB, Dalkin BL. Pilot study of changes in stretched penile length 3 months after radical retropubic prostatectomy. Urology. 2001;58:567
  2. Savoie M, Kim SS, Soloway MS. A prospective study measuring penile length in men treated with radical prostatectomy for prostate cancer. J Urol. 2003;169:1462
  3. Fraiman MC, Lepor H, McCullough AR. Changes in penile morphometrics in men with erectile dysfunction after nerve-sparing radical retropubic prostatectomy. Mol Urol. 1999;3:109
  4. Ciancio SJ, Kim ED. Penile fibrotic changes after radical retropubic prostatectomy. BJU Int. 2000;85:101
  5. McCullough AR, Lepor H. The loss of penile length and circumference in impotent men after nerve sparing radical prostatectomy. J Urol, suppl. 1998;159:98;abstract 376
  6. Mulhall JP. Penile length changes after radical prostatectomy. BJU Int. 2005;96:472
  7. Rosen RC, Riley A, Wagner G. The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49:822
  8. Cappellieri JC. Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function. Urology. 1999;54:346
  9. Chen J, Gefen A, Greenstein A, Matzkin H, Elad D. Predicting penile size during erection. Int J Impot Res. 2000;12:328
  10. Moreland RB. Is there a role of hypoxemia in penile fibrosis: a viewpoint presented to the Society for the Study of Impotence. Int J Impot Res. 1998;10:113
  11. Iacono F, Giannella R, Somma P, Manno G, Fusco F, Mirone V. Histological alterations in cavernous tissue after radical prostatectomy. J Urol. 2005;173:1673
  12. User HM, Hairston JH, Zelner DJ, McKenna KE, McVary KT. Penile weight and cell subtype specific changes in a post-radical prostatectomy model of erectile dysfunction. J Urol. 2003;169:1175
  13. Leungwattanakij S, Bivalacqua TJ, Usta MF, Yang DY, Hyun JS, Champion HC, et al. Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum. J Androl. 2003;24:239
  14. Laven BA, Alsikafi NF, Yang XJ, Brendler CB. Minor modifications in apical dissection of radical retropubic prostatectomy in patients with clinical stage T2 prostate cancer reduce positive surgical margin incidence. Urology. 2004;63:95

 See Editorial on page 376.

PII: S0022-5347(07)00767-7

doi: 10.1016/j.juro.2007.03.119

The Journal of Urology
Volume 178, Issue 2 , Pages 602-607 , August 2007

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