The Journal of Urology
Volume 177, Issue 4 , Pages 1298-1302 , April 2007

The Association Between Total Prostate Specific Antigen Concentration and Prostate Specific Antigen Velocity

  • Xiaoying Yu

      Affiliations

    • Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Stacy Loeb

      Affiliations

    • Department of Urology, Georgetown University School of Medicine, Washington, D.C.
    • ,
  • Kimberly A. Roehl

      Affiliations

    • Department of Psychiatry, Washington University, School of Medicine, St. Louis, Missouri
    • ,
  • Misop Han

      Affiliations

    • Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois
    • ,
  • William J. Catalona

      Affiliations

    • Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois
    • Corresponding Author InformationCorrespondence: Northwestern Medical Faculty Foundation, 675 North Saint Clair, 20-150, Chicago, Illinois 60611 (telephone: 312-695-4471).
    • Financial interest and/or other relationship with Beckman Coulter, Incorporated.

Received 3 July 2006

References 

  1. Catalona WJ, Smith DS, Ratliff TL, Dodds KM, Coplen DE, Yuan JJ, et al. Measurement of prostate-specific antigen in serum as a screening test for prostate cancer. N Engl J Med. 1991;324:1156
  2. Carter HB, Pearson JD, Metter EJ, Brant LJ, Chan DW, Andres R, et al. Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate disease. JAMA. 1992;267:2215
  3. D’Amico AV, Renshaw AA, Sussman B, Chen MH. Pretreatment PSA velocity and risk of death from prostate cancer following external beam radiation therapy. JAMA. 2005;294:440
  4. D’Amico AV, Chen MH, Roehl KA, Catalona WJ. Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy. N Engl J Med. 2004;351:125
  5. Smith DS, Catalona WJ. The nature of prostate cancer detected through prostate specific antigen based screening. J Urol. 1994;152:1732
  6. Thompson IM, Ankerst DP, Chi C, Goodman PJ, Tangen CM, Lucia MS, et al. Assessing prostate cancer risk: results from the Prostate Cancer Prevention Trial. J Natl Cancer Inst. 2006;98:529
  7. Sengupta S, Myers RP, Slezak JM, Bergstralh EJ, Zincke H, Blute ML. Preoperative prostate specific antigen doubling time and velocity are strong and independent predictors of outcomes following radical prostatectomy. J Urol. 2005;174:2191

 Supported by the Urological Research Foundation and Beckman Coulter, Incorporated.Study received Institutional Review Board approval.See Editorial on page 1225.

PII: S0022-5347(06)03227-7

doi: 10.1016/j.juro.2006.12.003

The Journal of Urology
Volume 177, Issue 4 , Pages 1298-1302 , April 2007

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