The Journal of Urology
Volume 177, Issue 2 , Pages 556-560 , February 2007

Changes in Urine Markers and Symptoms After Bladder Distention for Interstitial Cystitis

  • Deborah R. Erickson

      Affiliations

    • Department of Surgery, Division of Urology, University of Kentucky College of Medicine, Lexington, Kentucky
    • Corresponding Author InformationCorrespondence: Division of Urology, University of Kentucky College of Medicine, 800 Rose St., MS-269, Lexington, Kentucky 40536-0298 (telephone: 859-323-6679; FAX: 859-323-1944).
    • ,
  • Allen R. Kunselman

      Affiliations

    • Department of Health Evaluation Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    • ,
  • Christina M. Bentley

      Affiliations

    • Department of Health Evaluation Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    • ,
  • Kenneth M. Peters

      Affiliations

    • Department of Urology, William Beaumont Hospital, Royal Oak, Michigan
    • Financial interest and/or other relationship with Medtronic, Advanced Bionics, Indevus and Ortho McNeil.
    • ,
  • Eric S. Rovner

      Affiliations

    • Department of Surgery, Division of Urology, Medical University of South Carolina, Charleston, South Carolina
    • Financial interest and/or other relationship with Pfizer, Novartis, Q-Med, Indevus and Astellas.
    • ,
  • Laurence M. Demers

      Affiliations

    • Department of Pathology and Medicine, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    • ,
  • Marcia A. Wheeler

      Affiliations

    • Department of Surgery, Section of Urology, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Susan K. Keay

      Affiliations

    • Department of Medicine, Division of Infectious Diseases, University of Maryland School of Medicine and Veterans Affairs Medical Center, Baltimore, Maryland
    • Financial interest and/or other relationship with Merck Pharmaceuticals and Ortho-Clinical Diagnostics.

Received 1 March 2006

References 

  1. Cole EE, Scarpero HM, Dmochowski RR. Are patient symptoms predictive of the diagnostic and/or therapeutic value of hydrodistention?. Neurourol Urodyn. 2005;24:638
  2. Ottem DP, Teichman JM. What is the value of cystoscopy with hydrodistension for interstitial cystitis?. Urology. 2005;66:494
  3. Hanno PM, Wein AJ. Conservative therapy of interstitial cystitis. Semin Urol. 1991;9:143
  4. Erickson DR, Tomaszewski JE, Kunselman AR, Bentley CM, Peters KM, Rovner ES, et al. Do the National Institute of Diabetes and Digestive and Kidney Diseases cystoscopic criteria associate with other clinical and objective features of interstitial cystitis?. J Urol. 2005;173:93
  5. Hanno PM, Landis JR, Matthews-Cook Y, Kusek J, Nyberg L. The diagnosis of interstitial cystitis revisited: lessons learned from the National Institutes of Health Interstitial Cystitis Database study. J Urol. 1999;161:553
  6. Goin JE, Olaleye D, Peters KM, Steinert B, Habicht K, Wynant G. Psychometric analysis of the University of Wisconsin Interstitial Cystitis Scale: implications for use in randomized clinical trials. J Urol. 1998;159:1085
  7. Erickson DR, Xie SX, Bhavanandan VP, Wheeler MA, Hurst RE, Demers LM, et al. A comparison of multiple urine markers for interstitial cystitis. J Urol. 2002;167:2461
  8. Erickson DR. Urine markers of interstitial cystitis. Urology. 2001;57:15
  9. Keay SK, Szekely Z, Conrads TP, Veenstra TD, Barchi JJ, Zhang CO, et al. An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide. Proc Natl Acad Sci U S A. 2004;101:11803
  10. Hosseini A, Ehren I, Wiklund NP. Nitric oxide as an objective marker for evaluation of treatment response in patients with classic interstitial cystitis. J Urol. 2004;172:2261
  11. Chai TC, Zhang CO, Shoenfelt JL, Johnson HW, Warren JW, Keay SK. Bladder stretch alters urinary heparin-binding epidermal growth factor and antiproliferative factor in patients with interstitial cystitis. J Urol. 2000;163:1440
  12. Keay S, Kleinberg M, Zhang CO, Hise MK, Warren JW. Bladder epithelial cells from patients with interstitial cystitis produce an inhibitor of heparin-binding epidermal growth factor-like growth factor production. J Urol. 2000;164:2112
  13. Adam RM, Eaton SH, Estrada C, Nimgaonkar A, Shih SC, Smith LE, et al. Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol Genomics. 2004;20:36
  14. Zuraw BL, Sugimoto S, Parsons CL, Hugli T, Lotz M, Koziol J. Activation of urinary kallikrein in patients with interstitial cystitis. J Urol. 1994;152:874
  15. Erickson DR, Belchis DA, Dabbs DJ. Inflammatory cell types and clinical features of interstitial cystitis. J Urol. 1997;158:790
  16. Lynes WL, Flynn SD, Shortliffe LD, Stamey TA. The histology of interstitial cystitis. Am J Surg Pathol. 1990;14:969
  17. Sun Y, Chai TC. Effects of dimethyl sulphoxide and heparin on stretch-activated ATP release by bladder urothelial cells from patients with interstitial cystitis. BJU Int. 2002;90:381
  18. Sun Y, Chai TC. Up-regulation of P2X3 receptor during stretch of bladder urothelial cells from patients with interstitial cystitis. J Urol. 2004;171:448
  19. Rosamilia A, Clements JA, Dwyer PL, Kende M, Campbell DJ. Activation of the kallikrein kinin system in interstitial cystitis. J Urol. 1999;162:129
  20. Erickson DR, Kunselman AR, Bentley CM, Peters KM, Rovner ES, Demers LM, et al. Is urine methylhistamine a useful marker of interstitial cystitis?. J Urol. 2004;172:2256

 Supported by National Institute of Diabetes, Digestive and Kidney Diseases Grant RO1DK57281.

PII: S0022-5347(06)02512-2

doi: 10.1016/j.juro.2006.09.029

The Journal of Urology
Volume 177, Issue 2 , Pages 556-560 , February 2007

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