The Journal of Urology
Volume 177, Issue 1 , Pages 241-246 , January 2007

The Natural Progression and Remission of Erectile Dysfunction: Results From the Massachusetts Male Aging Study

  • Thomas G. Travison

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • Corresponding Author InformationCorrespondence: New England Research Institutes, 9 Galen St., Watertown, Massachusetts 02472 (telephone: 617-923-7747 ext. 552; FAX: 617-926-8246).
    • Nothing to disclose.
    • ,
  • Ridwan Shabsigh

      Affiliations

    • Department of Urology, Columbia University, New York, New York
    • Financial interest and/or other relationship with Pfizer, Lilly ICOS, Bayer/GSK, Boehringer Ingelheim, Solvay, AMS, Johnson & Johnson, Indevus, QuatRx and Schering.
    • ,
  • Andre B. Araujo

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • Nothing to disclose.
    • ,
  • Varant Kupelian

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • Nothing to disclose.
    • ,
  • Amy B. O’Donnell

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • Nothing to disclose.
    • ,
  • John B. McKinlay

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • Nothing to disclose.

Received 17 February 2006

References 

  1. Aytac IA, McKinlay JB, Krane RJ. The likely worldwide increase of erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999;84:50
  2. NIH Consensus ConferenceNIH Consensus Development Panel on Impotence. Impotence. JAMA. 1993;270:83
  3. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol. 1994;151:54
  4. Prins J, Blanker MH, Bohnen AM, Thomas S, Bosch JL. Prevalence of erectile dysfunction: a systematic review of population-based studies. Int J Impot Res. 2002;14:422
  5. Shabsigh R, Perelman MA, Lockhart DC, Lue TF, Broderick GA. Health issues of men: prevalence and correlates of erectile dysfunction. J Urol. 2005;174:662
  6. Thompson IM, Tangen CM, Goodman PJ, Probstfield JL, Moinpour CM, Coltman CA. Erectile dysfunction and subsequent cardiovascular disease. JAMA. 2005;294:2996
  7. Masson P, Lambert SM, Brown M, Shabsigh R. PDE-5 inhibitors: current status and future trends. Urol Clin North Am. 2005;32:511
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  10. Esposito K, Giugliano F, DiPalo C, Guigliano G, Marfella R, D’Andrea F, et al. Effect of lifestyle changes on erectile dysfunction in obese men: a randomized controlled trial. JAMA. 2004;291:2978
  11. Shabsigh R, Perelman M, Laumann EO, Lockhart DC. Drivers and barriers to seeking treatment for erectile dysfunction, a comparison of six countries. BJU Int. 2004;94:1055
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  13. McCulloch DK, Young RJ, Prescott RJ, Campbell IW, Clarke BF. The natural history of impotence in diabetic men. Diabetologia. 1984;26:437
  14. Kleinman KP, Feldman HA, Johannes CB, Derby CA, McKinlay JB. A new surrogate variable for erectile dysfunction status in the Massachusetts Male Aging Study. J Clin Epidemiol. 2000;53:71
  15. O’Donnell AB, Araujo AB, Goldstein IM, McKinlay JB. The validity of a single-question self-report of erectile dysfunction. J Gen Intern Med. 2005;20:515
  16. Radloff LS. The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385
  17. Willett WC, Reynolds RD, Cottrell-Hoehner S, Sampson L, Browne ML. Validation of a semi-quantitative food frequency questionnaire: comparison with a 1-year diet record. J Am Diet Assoc. 1987;87:43
  18. McKinlay JB, Feldman HA. Age-related variation in sexual activity and interest in normal men: results from the Massachusetts Male Aging Study. In:  Rossi AS editors. Sexuality Across the Life Course: Proceedings of the MacArthur Foundation Research Network on Successful Mid-Life Development. New York: University of Chicago Press; 1994261;
  19. Fisher WA, Rosen RC, Eardley I, Niederberger C, Nadel A, Kaufman J, et al. The Multinational Men’s Attitudes of Life Events and Sexuality (MALES) study phase II: understanding PDE5 inhibitor treatment seeking patterns, among men with erectile dysfunction. J Sex Med. 2004;1:150
  20. Derby CA, Araujo AB, Johannes CB, Feldman HA, McKinlay JB. Measurement of erectile dysfunction in population-based studies: the use of a single question self-assessment in the Massachusetts Male Aging Study. Int J Impot Res. 2000;12:197

 Study received Institutional Review Board approval from the New England Research Institutes.

 Supported by the National Institutes of Health (National Institute of Diabetes and Digestive and Kidney Diseases Grants DK44995 and DK54315, and National Institute on Aging Grant AG04673).

 Editor’s Note: This article is the third of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 410 and 411.

PII: S0022-5347(06)02152-5

doi: 10.1016/j.juro.2006.08.108

The Journal of Urology
Volume 177, Issue 1 , Pages 241-246 , January 2007

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