The Journal of Urology
Volume 176, Issue 2 , Pages 564-568 , August 2006

Long-Term Outcome Following Radical Prostatectomy in Men With Clinical Stage T3 Prostate Cancer

  • Brett S. Carver

      Affiliations

    • Corresponding Author InformationCorrespondence: Department of Urology, Sidney Kimmel Center for Prostate and Urologic Cancers, 353 East 68th St., New York, New York 10021 (telephone: 212-639-8266; FAX: 212-988-0759).
    • ,
  • Fernando J. Bianco Jr.
    • ,
  • Peter T. Scardino

      Affiliations

    • Financial interest and/or other relationship with Steba Pharmaceuticals, Oncovance Inc., Merck, Sanofi Aventis, National Cancer Institute, National Institutes of Health, Prostate Cancer Foundation, AstraZeneca, Penguin Putnam Inc. and Nature Urology.
    • ,
  • James A. Eastham

      Affiliations

    • Financial interest and/or other relationship with Novartis.

Received 15 August 2005

References 

  1. Ward JF , Slezak JM , Blute ML , Bergstralh EJ , Zincke H . Radical prostatectomy for clinically advanced (cT3) prostate cancer since the advent of prostate-specific antigen testing (15-year outcome) . BJU Int . 2005;95:751
  2. Zagars GK , von Eschenbach AC , Ayala AG . Prognostic factors in prostate cancer. Analysis of 874 patients treated with radiation therapy . Cancer . 1993;72:1709
  3. Hanks GE , Krall JM , Hanlon AL , Asbell SO , Pilepich MV , Owen JB . Patterns of Care and RTOG studies in prostate cancer (long-term survival, hazard rate observations, and possibilities of cure) . Int J Radiat Oncol Biol Phys . 1994;28:39
  4. Zagars GK , Johnson DE , von Eschenbach AC , Hussey DH . Adjuvant estrogen following radiation therapy for stage C adenocarcinoma of the prostate (long-term results of a prospective randomized study) . Int J Radiat Oncol Biol Phys . 1988;14:1085
  5. Granfors T , Modig H , Damber JE , Tomic R . Combined orchiectomy and external radiotherapy versus radiotherapy alone for nonmetastatic prostate cancer with or without pelvic lymph node involvement (a prospective randomized study) . J Urol . 1998;159:2030
  6. Bolla M , Gonzalez D , Warde P , Dubois JB , Mirimanoff RO , Storme G , et al.   Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin . N Engl J Med . 1997;337:295
  7. Crook JM , Perry GA , Robertson S , Esche BA . Routine prostate biopsies following radiotherapy for prostate cancer (results for 226 patients) . Urology . 1995;45:624
  8. Zietman AL , Westgeest JC , Shipley WU . Radiation-based approaches to the management of T3 prostate cancer . Semin Urol Oncol . 1997;15:230
  9. Lerner SE , Blute ML , Zincke H . Extended experience with radical prostatectomy for clinical stage T3 prostate cancer (outcome and contemporary morbidity) . J Urol . 1995;154:1447
  10. Van den Ouden D , Hop WC , Schroder FH . Progression in and survival of patients with locally advanced prostate cancer (T3) treated with radical prostatectomy as monotherapy . J Urol . 1998;160:1392
  11. Witjes WP , Schulman CC , Debruyne FM  The European Study Group on Neoadjuvant Treatment of Prostate Cancer . Preliminary results of a prospective randomized study comparing radical prostatectomy versus radical prostatectomy associated with neoadjuvant hormonal combination therapy in T2-T3 N0 M0 prostatic carcinoma . Urology . 1997;49:65
  12. Amling CL , Blute ML , Bergstralh EJ , Slezak JM , Martin SK , Zincke H . Preoperative androgen-deprivation therapy for clinical stage T3 prostate cancer . Semin Urol Oncol . 1997;15:222
  13. Soloway MS , Sharifi R , Wajsman Z , McLeod D , Wood DP , Puras-Baez A . Randomized prospective study comparing radical prostatectomy alone versus radical prostatectomy preceded by androgen blockade in clinical stage B2 (T2bNxM0) prostate cancer . J Urol . 1995;154:424
  14. Mordkin RM , Hayes WS , Kuettel MR , Lynch JH . Management of locally advanced prostate cancer . Oncology . 1996;10:1289
  15. Pilepich MV , Caplan R , Byhardt RW , Lawton CA , Gallagher MJ , Mesic JB , et al.   Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy (report of Radiation Therapy Oncology Group Protocol 85-31) . J Clin Oncol . 1997;15:1013
  16. Bolla M , Collette L , Blank L , Warde P , Dubois JB , Mirimanoff RO , et al.   Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EROTC study) (a phase III randomised trial) . Lancet . 2002;360:103
  17. Cadeddu JA , Partin AW , Epstein JI , Walsh PC . Stage D1 (T1-3, N1-3, M0) prostate cancer (a case-controlled comparison of conservation treatment versus radical prostatectomy) . Urology . 1997;50:251
  18. Coen JJ , Zietman AL , Thakral H , Shipley WU . Radical radiation for localized prostate cancer (local persistence of disease results in a late wave of metastases) . J Clin Oncol . 2002;20:3199
  19. Thompson IM , Tangen C , Basler J , Crawford ED . Impact of previous local treatment for prostate cancer on subsequent metastatic disease . J Urol . 2002;168:1008
  20. Konety BR , Eastham JA , Reuter VE , Scardino PT , Donat SM , Dalbagni G , et al.   Feasibility of radical prostatectomy after neoadjuvant chemohormonal therapy for patients with high risk or locally advanced prostate cancer (results of a phase I/II study) . J Urol . 2004;171:709

 See Editorial on page 437.

PII: S0022-5347(06)00781-6

doi: 10.1016/j.juro.2006.03.093

The Journal of Urology
Volume 176, Issue 2 , Pages 564-568 , August 2006

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