The Journal of Urology
Volume 176, Issue 1 , Pages 217-221 , July 2006

A Prospective Study of Risk Factors for Erectile Dysfunction

  • Constance G. Bacon

      Affiliations

    • Department of Nutrition, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Department of Health and Social Behavior, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • ,
  • Murray A. Mittleman

      Affiliations

    • Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Beth Israel Deaconess Medical Center, Boston, Massachusetts
    • ,
  • Ichiro Kawachi

      Affiliations

    • Department of Health and Social Behavior, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Department of Medicine, Brigham and Woman’s Hospital and Harvard Medical School, Boston, Massachusetts
    • ,
  • Edward Giovannucci

      Affiliations

    • Department of Nutrition, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Department of Medicine, Brigham and Woman’s Hospital and Harvard Medical School, Boston, Massachusetts
    • ,
  • Dale B. Glasser

      Affiliations

    • Sexual Health Team, Pfizer, Inc, New York, New York
    • Financial interest and/or other relationship with Pfizer.
    • ,
  • Eric B. Rimm

      Affiliations

    • Department of Nutrition, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, Boston, Massachusetts
    • Department of Medicine, Brigham and Woman’s Hospital and Harvard Medical School, Boston, Massachusetts
    • Corresponding Author InformationCorrespondence and requests for reprints: Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave., Boston, Massachusetts 02115 (telephone: 617-432-1843; FAX: 617-432-2435).

Received 18 August 2005

References 

  1. Marumo K , Nakashima J , Murai M . Age-related prevalence of erectile dysfunction in Japan (assessment by the International Index of Erectile Dysfunction) . Int J Urol . 2001;8:53
  2. McKinlay JB . The worldwide prevalence and epidemiology of erectile dysfunction . Int J Impot Res . 2000;12:S6
  3. Moreira ED , Lisboa Lobo CF , Villa M , Nicolosi A , Glasser DB . Prevalence and correlates of erectile dysfunction in Salvador, northeastern Brazil (a population-based study) . Int J Impot Res . 2002;14:S3
  4. Blanker MH , Bohnen AM , Groeneveld FP , Bernsen RM , Prins A , Thomas S , et al.   Correlates for erectile and ejaculatory dysfunction in older Dutch men (a community-based study) . J Am Geriatr Soc . 2001;49:436
  5. Martin-Morales A , Sanchez-Cruz JJ , Saenz de Tejada I , Rodriguez-Vela L , Jimenez-Cruz JF , Burgos-Rodriguez R . Prevalence and independent risk factors for erectile dysfunction in Spain (results of the Epidemiologia de la Disfuncion Erectil Masculina Study) . J Urol . 2001;166:569
  6. Mirone V , Imbimbo C , Bortolotti A , Di Cintio E , Colli E , Landoni M , et al.   Cigarette smoking as risk factor for erectile dysfunction (results from an Italian epidemiological study) . Eur Urol . 2002;41:294
  7. Feldman HA , Johannes CB , Derby CA , Kleinman KP , Mohr BA , Araujo AB , et al.   Erectile dysfunction and coronary risk factors (prospective results from the Massachusetts male aging study) . Prev Med . 2000;30:328
  8. Aytac IA , Araujo AB , Johannes CB , Kleinman KP , McKinlay JB . Socioeconomic factors and incidence of erectile dysfunction (findings of the longitudinal Massachusetts Male Aging Study) . Soc Sci Med . 2000;51:771
  9. Laumann EO , Paik A , Rosen RC . Sexual dysfunction in the United States (prevalence and predictors) . JAMA . 1999;281:537
  10. Pinnock CB , Stapleton AM , Marshall VR . Erectile dysfunction in the community (a prevalence study) . Med J Aust . 1999;171:353
  11. Moreira ED , Lbo CF , Diament A , Nicolosi A , Glasser DB . Incidence of erectile dysfunction in men 40 to 69 years old (results from a population-based cohort study in Brazil) . Urology . 2003;61:431
  12. Shiri R , Koskimaki J , Hakama M , Hakkinen J , Huhtala H , Tammela TL , et al.   Effect of life-style factors on incidence of erectile dysfunction . Int J Impot Res . 2004;16:389
  13. Rimm EB , Giovannucci EL , Willett WC , Colditz GA , Ascherio A , Rosner B , et al.   Prospective study of alcohol consumption and risk of coronary disease in men . Lancet . 1991;338:464
  14. Chasan-Taber S , Rimm EB , Stampfer MJ , Spiegelman D , Colditz GA , Giovannucci E , et al.   Reproducibility and validity of a self-administered physical activity questionnaire for male health professionals . Epidemiology . 1996;7:81
  15. Feldman HA , Goldstein I , Hatzichristou DG , Krane RJ , McKinlay JB . Impotence and its medical and psychosocial correlates (results of the Massachusetts Male Aging Study) . J Urol . 1994;151:54
  16. Mak R , De Backer G , Kornitzer M , De Meyer JM . Prevalence and correlates of erectile dysfunction in a population-based study in Belgium . Eur Urol . 2002;41:132
  17. Bacon CG , Mittleman MA , Kawachi I , Giovannucci E , Glasser DB , Rimm EB . Sexual function in men older than 50 years of age (results from the health professionals follow-up study) . Ann Intern Med . 2003;139:161
  18. Williams IL , Wheatcroft SB , Shah AM , Kearney MT . Obesity, atherosclerosis and the vascular endothelium (mechanisms of reduced nitric oxide bioavailability in obese humans) . Int J Obes Relat Metab Disord . 2002;26:754
  19. Taddei S , Galetta F , Virdis A , Ghiadoni L , Salvetti G , Franzoni F , et al.   Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes . Circulation . 2000;101:2896
  20. Litwin MS , Melmed GY , Nakazon T . Life after radical prostatectomy (a longitudinal study) . J Urol . 2001;166:587

 Study received institutional review board approval.

 Supported by Pfizer, Inc, and by Grants CA55075 and HL35464 from the National Institutes of Health.

PII: S0022-5347(06)00589-1

doi: 10.1016/S0022-5347(06)00589-1

The Journal of Urology
Volume 176, Issue 1 , Pages 217-221 , July 2006

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