The Journal of Urology
Volume 176, Issue 1 , Pages 222-226 , July 2006

Erectile Dysfunction as a Predictor of the Metabolic Syndrome in Aging Men: Results From the Massachusetts Male Aging Study

  • Varant Kupelian

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • ,
  • Ridwan Shabsigh

      Affiliations

    • Department of Urology, Columbia University, New York, New York
    • Financial interest and/or other relationship with Pfizer, Lilly Icos, Boehringer Ingelheim, Bayer/GSK/Schering Plough, Solvay, American Medical Systems, Schering AG and Johnson & Johnson.
    • ,
  • Andre B. Araujo

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • ,
  • Amy B. O’Donnell

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • ,
  • John B. McKinlay

      Affiliations

    • New England Research Institutes, Watertown, Massachusetts
    • Corresponding Author InformationCorrespondence: New England Research Institutes, 9 Galen St., Watertown, Massachusetts 02472 (telephone: 617-923-7747 ext. 512; FAX: 617-924-0968).

Received 20 September 2005

References 

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  10. O’Donnell AB , Araujo AB , McKinlay JB . The health of normally aging men (The Massachusetts Male Aging Study (1987–2004)) . Exp Gerontol . 2004;39:975
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  12. O’Donnell AB , Araujo AB , Goldstein I , McKinlay JB . The validity of a single-question self-report of erectile dysfunction . J Gen Intern Med . 2005;20:515
  13. Kleinman KP , Feldman HA , Johannes CB , Derby CA , McKinlay JB . A new surrogate variable for erectile dysfunction status in the Massachusetts male aging study . J Clin Epidemiol . 2000;53:71
  14. Bansal TC , Guay AT , Jacobson J , Woods BO , Nesto RW . Incidence of metabolic syndrome and insulin resistance in a population with organic erectile dysfunction . J Sex Med . 2005;2:96
  15. Matfin G , Jawa A , Fonseca VA . Erectile dysfunction (interrelationship with the metabolic syndrome) . Curr Diab Rep . 2005;5:64
  16. Jeremy JY , Angelini GD , Khan M , Mikhailidis DP , Morgan RJ , Thompson CS , et al.   Platelets, oxidant stress and erectile dysfunction (an hypothesis) . Cardiovasc Res . 2000;46:50
  17. Kirby M , Jackson G , Betteridge J , Friedli K . Is erectile dysfunction a marker for cardiovascular disease? . Int J Clin Pract . 2001;55:614
  18. Billups KL , Kaiser DR , Kelly AS , Wetterling RA , Tsai MY , Hanson N , et al.   Relation of C-reactive protein and other cardiovascular risk factors to penile vascular disease in men with erectile dysfunction . Int J Impot Res . 2003;15:231
  19. Kaiser DR , Billups K , Mason C , Wetterling R , Lundberg JL , Bank AJ . Impaired brachial artery endothelium-dependent and -independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease . J Am Coll Cardiol . 2004;43:179
  20. Matthews JN , Altman DG . Statistics notes. Interaction 2: Compare effect sizes not P values . BMJ . 1996;313:808

 Supported by Grant AG04763 from the National Institute on Aging, and Grants DK51345 and DK44995 from the National Institute of Diabetes and Digestive and Kidney Diseases.

PII: S0022-5347(06)00503-9

doi: 10.1016/S0022-5347(06)00503-9

The Journal of Urology
Volume 176, Issue 1 , Pages 222-226 , July 2006

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