The Journal of Urology
Volume 176, Issue 1 , Pages 119-124 , July 2006

How Does the Pre-Massage and Post-Massage 2-Glass Test Compare to the Meares-Stamey 4-Glass Test in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome?

  • J. Curtis Nickel

      Affiliations

    • Queen’s University, Kingston, Ontario, Canada
    • Corresponding Author InformationCorrespondence: Department of Urology, Queen’s University, Kingston General Hospital, Kingston, Ontario, Canada K7L 2V7 (telephone: 613-548-2497; FAX: 613-545-1970).
    • Financial interest and/or other relationship with Glaxo Smith Kline Canada, Merck Frosst Canada, Farr Laboratories, Sanofi-Aventis and Janssen-Ortho Canada.
    • ,
  • Daniel Shoskes

      Affiliations

    • Cleveland Clinic Florida, Weston, Florida
    • Financial interest and/or other relationship with Farr Laboratories, Nanobac Labs and Triurol.
    • ,
  • Yanlin Wang

      Affiliations

    • University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • Nothing to disclose.
    • ,
  • Richard B. Alexander

      Affiliations

    • Veterans Affairs Maryland Health Care System and University of Maryland School of Medicine, Baltimore
    • Financial interest and/or other relationship with Merck.
    • ,
  • Jackson E. Fowler Jr.

      Affiliations

    • University of Mississippi Health Science Center, Jackson, Mississippi
    • Nothing to disclose.
    • ,
  • Scott Zeitlin

      Affiliations

    • David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, Brigham
    • Financial interest and/or other relationship with Lilly Icos, Boehringer Ingelheim, Ortho McNeil and Pfizer.
    • ,
  • Michael P. O’Leary

      Affiliations

    • Women’s Hospital, Boston, Massachusetts
    • Financial interest and/or other relationship with Glaxo, Sanofi Aventis and BIPI.
    • ,
  • Michel A. Pontari

      Affiliations

    • Temple University, Philadelphia, Pennsylvania
    • Financial interest and/or other relationship with Merck & Co., Sanofi, Pfizer, Roche and Wyeth.
    • ,
  • Anthony J. Schaeffer

      Affiliations

    • Northwestern University, Chicago, Illinois
    • Financial interest and/or other relationship with Bayer, Pfizer, McNeil Consumer & Specialty Pharmaceuticals, National Institutes of Health, Boehringer Ingelheim and BMJ Publishing Group.
    • ,
  • J. Richard Landis

      Affiliations

    • University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • Financial interest and/or other relationship with Alza Pharmaceuticals, Pfizer (formerly Pharmacia), Bristol Myers Squibb and Sanofi-Synthelabo.
    • ,
  • Leroy Nyberg

      Affiliations

    • National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
    • Nothing to disclose.
    • ,
  • John W. Kusek

      Affiliations

    • National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
    • Nothing to disclose.
    • ,
  • Kathleen J. Propert

      Affiliations

    • University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • Nothing to disclose.
    • ,
  • Chronic Prostatitis Collaborative Research Network Study Group

Received 25 July 2005

References 

  1. Nickel JC . Prostatitis (an historical perspective) . In: Textbook of Prostatitis . Oxford: ISIS Medical Media Ltd; 1999;p. 3–18
  2. Hitchens AP , Brown CP . The bacteriology of chronic prostatitis . Am J Public Health . 1913;3:884
  3. Von Lackum WH . The infected prostate . Proc Staff Meet Mayo Clin . 1928;3:14
  4. Nickel AJ . The bacteriology of chronic prostatitis and seminal vesiculitis and elective localization of the bacteria as isolated . J Urol . 1930;24:343
  5. Stamey TA , Govan DE , Palmer JM . The localization and treatment of urinary tract infections (the role of bactericidal urine levels as opposed to serum levels) . Medicine . 1965;44:1
  6. Meares EM , Stamey TA . Bacteriologic localization patterns in bacterial prostatitis and urethritis . Invest Urol . 1968;5:492
  7. McNaughton Collins M , Fowler FJ , Elliott DB , Albertson PC , Barry MJ . Diagnosing and treating chronic prostatitis (do urologists use the four-glass test?) . Urology . 2000;55:403
  8. Weidner W , Ebner H . Cytological analysis of urine after prostatic massage (VB3) (a new technique for discriminating diagnosis of prostatitis) . In:  Brunner H ,  Krause W ,  Rothaug CF ,  Weidner E editor. Chronic Prostatitis . Stuttgart, Germany: Schattauer; 1985;p. 141–151
  9. Nickel JC . Effective office management of chronic prostatitis . Urol Clin North Am . 1998;25:677
  10. Nickel JC . The Pre and Post Massage Test (PPMT) (a simple screen for prostatitis) . Tech Urol . 1997;3:38
  11. Ludwig M , Schroeder-Printzen I , Ludecke G , Weidner W . Comparison of expressed prostatic secretions with urine after prostatic massage—a means to diagnose chronic prostatitis/inflammatory chronic pelvic pain syndrome . Urology . 2000;55:175
  12. Seiler D , Zbinden R , Hauri D , John H . Four-glass or two glass test for chronic prostatitis . Urologe A . 2003;42:238
  13. Schaeffer AJ , Landis JR , Knauss JS , Propert KJ , Alexander RB , Litwin MS , et al.   Demographic and clinical characteristics of men with chronic prostatitis (the National Institutes of Health Chronic Prostatitis Cohort Study) . J Urol . 2002;168:593
  14. Drach GW , Fair WR , Meares EM , Stamey TA . Classification of benign diseases associated with prostatic pain (prostatitis or prostatodynia?) . J Urol . 1978;120:266
  15. Krieger JN , Nyberg L , Nickel JC . NIH consensus definition and classification of prostatitis . JAMA . 1999;282:236
  16. Nickel JC , Alexander RB , Schaeffer AJ , Landis JR , Knauss JS , Propert KJ . Leukocytes and bacteria in men with chronic prostatitis/chronic pelvic pain syndrome compared to asymptomatic controls . J Urol . 2003;170:818
  17. Schaeffer AJ , Datta NS , Fowler JE , Krieger JN , Litwin MS , Nadler RB . Advances in the diagnosis and treatment of prostatitis (overview summary statement) . Urology . 2003;60(suppl):1
  18. Bjerklund Johansen TE , Gruneberg RN , Guibert J , Hofstetter A , Lobel B , Naber KG , et al.   The role of antibiotics in the treatment of chronic prostatitis (a consensus statement) . Eur Urol . 1998;34:457
  19. Pontari MA , Ruggieri MR . Mechanisms in prostatitis/chronic pelvic pain syndrome . J Urol . 2004;172:839

 Supported by cooperative agreements (U01 DK53572, U01 DK53730, U01 DK53736, U01 DK53734, U01 DK53732, U01 DK53746 and U01 DK53738) from the National Institute of Diabetes and Digestive and Kidney Diseases.Supported by the National Center for Minority Health and Health Disparities, National Institutes of Health.Study received Institutional Review Board approval from all participating institutions.Editor’s Note: This article is the third of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 418 and 419.

PII: S0022-5347(06)00498-8

doi: 10.1016/S0022-5347(06)00498-8

The Journal of Urology
Volume 176, Issue 1 , Pages 119-124 , July 2006

Article Tools