The Journal of Urology
Volume 170, Issue 3 , Pages 835-839 , September 2003

Effectiveness Of Intravesical Resiniferatoxin For Anticholinergic Treatment Refractory Detrusor Overactivity Due To Nonspinal Cord Lesions

  • HANN-CHORNG KUO

      Affiliations

    • Corresponding Author InformationCorresponding author and requests for reprints: Department of Urology, Buddhist Tzu Chi General Hospital, 707, Sec. 3, Chung Yang Rd., Hualien, Taiwan (telephone: 886-3-8561825, ext. 2117; FAX: 886-3-8560794).

,Accepted 14 March 2003.

REFERENCES 

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  2. Silva C , Ribeiro MJ , Cruz F . The effect of intravesical resiniferatoxin in patients with idiopathic detrusor instability suggests that involuntary detrusor contractions are triggered by C-fiber input . J Urol . 2002;168:575
  3. Fowler CJ , Jewkes D , McDonald WI , Lynn B , de Groat WC . Intravesical capsaicin for neurogenic bladder dysfunction . Lancet . 1992;339:1239
  4. Fowler CJ , Beck RO , Gerrard S , Betts CD , Fowler CG . Intravesical capsaicin for treatment of detrusor hyperreflexia . J Neurol Neurosurg Psych . 1994;57:169
  5. Cruz F , Guimaraes M , Silva C , Reis M . Suppression of bladder hyperreflexia by intravesical resiniferatoxin . Lancet . 1997;350:640
  6. Lazzeri M , Beneforti P , Turini D . Urodynamic effects of intravesical resiniferatoxin in humans: preliminary results in stable and unstable detrusor . J Urol . 1997;158:2093
  7. Lazzeri M , Spinelli M , Beneforti P , Zanollo A , Turini D . Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord diseases . Scand J Urol Nephrol . 1998;32:331
  8. Lazzeri M , Beneforti P , Spinelli M , Zanollo A , Barbagli G , Turini D . Intravesical resiniferatoxin for the treatment of hypersensitive disorders: a randomized placebo controlled study . J Urol . 2000;164:676
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  11. Cruz F , Guimarães M , Silva C , Rio ME , Coimbra A , Reis M . Desensitization of bladder sensory fibers by intravesical capsaicin has long lasting clinical and urodynamic effects in patients with hyperactive or hypersensitive bladder dysfunction . J Urol . 1997;157:585
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  14. De Ridder D , Van Poppel H , Baert L . Intravesical capsaicin inhibits autonomic dysreflexia in patients with spinal cord injury . Neurourol Urodyn . 1996;15:373
  15. Lazzeri M , Spinelli M , Beneforti P , Zanollo A , Turini D . Urodynamic assessment during intravesical infusion of capsaicin for the treatment of refractory detrusor hyperreflexia . Spinal Cord . 1999;37:440
  16. Cruz F , Guimaraes M , Silva C , Reis M . Suppression of bladder hyperreflexia by intravesical resiniferatoxin . Lancet . 1997;350:640
  17. Griffiths D , Hofner K , van Mastrigt R , Rollema HJ , Spangberg A , Gleason D . Standardization of terminology of lower urinary tract function: pressure-flow studies of voiding, urethral resistance, and urethral obstruction, International Continence Society Subcommittee on Standardization of Terminology of Pressure-Flow Studies . Neurourol Urodyn . 1997;16:1
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 Editor’s Note: This article is the fifth of 5 published in this issue for which category 1 CME credits can be earned. Instructions for obtaining credits are given with the questions on pages 960 and 961.Study received institutional ethical and human subject protection committee approval.

PII: S0022-5347(05)63244-2

doi: 10.1097/01.ju.0000081652.31524.27

The Journal of Urology
Volume 170, Issue 3 , Pages 835-839 , September 2003

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