The Journal of Urology
Volume 175, Issue 4 , Pages 1359-1363 , April 2006

Penile Carcinoma in Patients With Genital Lichen Sclerosus: A Multicenter Survey

  • G. Barbagli

      Affiliations

    • Center for Urethral and Genitalia Reconstructive Surgery, Florence, Italy
    • ,
  • E. Palminteri

      Affiliations

    • Center for Urethral and Genitalia Reconstructive Surgery, Florence, Italy
    • ,
  • F. Mirri

      Affiliations

    • Arezzo, Sezione di Anatomia Patologica, Ospedale S. Maria alla Gruccia, Florence, Italy
    • ,
  • G. Guazzoni

      Affiliations

    • Montevarchi, San Raffaele-Vita Salute Hospital and University, Florence, Italy
    • ,
  • D. Turini

      Affiliations

    • Milano and Department of Urology, Santa Chiara Firenze, Florence, Italy
    • ,
  • M. Lazzeri

      Affiliations

    • Milano and Department of Urology, Santa Chiara Firenze, Florence, Italy
    • Corresponding Author InformationCorrespondence: Department of Urology, Santa Chiara Firenze, P.za Indipendenza, 11, 50129 Florence, Italy (telephone: +39.05550381/+39.0555038517; FAX: +39.055480676

Received 15 May 2005

References 

  1. Powell JJ , Wojnarowska F . Lichen sclerosus . Lancet . 1999;353:1777
  2. Barbagli G , Lazzeri M , Palminteri E , Turini D . Lichen sclerosis of male genitalia involving anterior urethra . Lancet . 1999;354:429
  3. Depasquale I , Park AJ , Bracka A . The treatment of balanitis xerotica obliterans . BJU Int . 2000;86:459
  4. Barbagli G , Palminteri E , Lazzeri M , Turini D . Lichen sclerosus of the male genitalia . Contemp Urol . 2001;13:47
  5. von Krogh G , Horenblas S . Diagnosis and clinical presentation of premalignant lesions of the penis . Scand J Urol Nephrol Suppl . 2000;205:201
  6. Nasca MR , Innocenzi D , Micali G . Penile cancer among patients with genital lichen sclerosus . J Am Acad Dermatol . 1999;41:911
  7. Powell J , Robson A , Cranston D , Wojnarowska F , Turner R . High incidence of lichen sclerosus in patients with squamous cell carcinoma of the penis . Br J Dermatol . 2001;145:85
  8. Porter WM , Francis N , Hawkins D , Dinneen M , Bunker CB . Penile intraepithelial neoplasia (clinical spectrum and treatment of 35 cases) . Br J Dermatol . 2002;147:1159
  9. Cubilla AL , Velazquez EF , Young RH . Pseudohyperplastic squamous cell carcinoma of the penis associated with Lichen sclerosus. An extremely well-differentiated, nonverruciform neoplasm that preferentially affects the foreskin and is frequently misdiagnosed (a report of 10 cases of a distinctive clinicopathologic entity) . Am J Surg Pathol . 2004;28:895
  10. Pride HB , Miller OF , Tyler WB . Penile squamous cell carcinoma arising from balanitis xerotica obliterans . J Am Acad Dermatol . 1993;29:469
  11. Paricio Rubio JF , Revenga AF , Alfaro TJ , Ramirez GT . Squamous cell carcinoma of the penis arising on lichen sclerosus et atrophicus . J Eur Acad Dermatol Venereol . 1999;12:153
  12. Cupp MR , Malek RS , Goellner JR , Smith TF , Espy MJ . The detection of human papillomavirus deoxyribonucleic acid in intraepithelial, in situ, verrucous and invasive carcinoma of the penis . J Urol . 1995;154:1024
  13. Perceau G , Derancourt C , Clavel C , Durlach A , Pluot M , Lardennois B , et al.   Lichen sclerosus is frequently present in penile squamous cell carcinomas but is not always associated with oncogenic human papillomavirus . Br J Dermatol . 2003;148:934
  14. Meffert JJ , Davis BM , Grimwood RE . Lichen sclerosus . J Am Acad Dermatol . 1995;32:393
  15. Velazquez EF , Cubilla AL . Lichen sclerosus in 68 patients with squamous cell carcinoma of the penis (frequent atypias and correlation with special carcinoma variants suggests a precancerous role) . Am J Surg Pathol . 2003;27:1448
  16. Campus GV , Alia F , Bosincu L . Squamous cell carcinoma and lichen sclerosus et atrophicus of the prepuce . Plast Reconstr Surg . 1992;89:962
  17. Micali G , Nasca MR , Innocenzi D . Lichen sclerosus of the glans is significantly associated with penile carcinoma . Sex Transm Inf . 2001;77:226
  18. Clemmensen OJ , Krogh J , Petri M . The histologic spectrum of prepuces from patients with phimosis . Am J Dermopathol . 1988;10:104
  19. Mallon E , Hawkins D , Dinneen M , Francis N , Fearfield L , Newson R , et al.   Circumcision and genital dermatoses . Arch Dermatol . 2000;136:350
  20. Bailis SA . Association between invasive squamous cell carcinoma and Lichen sclerosus et atrophicus . Scand J Urol Nephrol . 2001;35:435

PII: S0022-5347(05)00735-4

doi: 10.1016/S0022-5347(05)00735-4

The Journal of Urology
Volume 175, Issue 4 , Pages 1359-1363 , April 2006

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